Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 3/20 | 0.38 |
| ▸ | ICMT | O60725 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6480466 | 1.00 | TSHR (0.39) | TSHRATMTDP1L3MBTL1TACR1 | |
| SCHEMBL6492793 | 0.84 | CA1 (0.43) | TSHRATMTDP1L3MBTL1CYP2C19 | |
| SCHEMBL6492790 | 0.84 | CA1 (0.43) | TSHRATMTDP1L3MBTL1CYP2C19 | |
| SCHEMBL7930882 | 0.84 | ALOX15 (0.49) | TSHRATMTDP1L3MBTL1CYP2C19 | |
| SCHEMBL6120248 | 0.79 | TSHR (0.47) | TSHRTDP1L3MBTL1TACR1CYP2C19 | |
| SCHEMBL6120592 | 0.79 | TSHR (0.47) | TSHRTDP1L3MBTL1TACR1CYP2C19 | |
| SCHEMBL1569297 | 0.77 | TSHR (0.48) | TSHRTACR1CYP2C19SLC1A1HTT | |
| SCHEMBL3164232 | 0.77 | TSHR (0.48) | TSHRTACR1CYP2C19SLC1A1HTT | |
| SCHEMBL29337772 | 0.77 | TSHR (0.48) | TSHRTACR1CYP2C19SLC1A1HTT | |
| SCHEMBL31399488 | 0.76 | L3MBTL1 (0.50) | TSHRTDP1L3MBTL1TRPV1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239804-A1 | Method for improved chemical synthesis of guanidinium alkaloids | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2005-10-27 | — | — | US | disclosed |
| CN-1487942-A | Hexahydropyrrolo [1,2-c] pyrimidines as antiviral, antifungal and/or antitumor agents | �Ϻ���ͨ��ѧ | 2004-04-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239804-A1 | Method for improved chemical synthesis of guanidinium alkaloids | PAICS, TYMS, IMPDH1 | TSHR 3398/4885ATM 4193/4885TDP1 904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.