Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL649760 | 1.00 | C5AR1 (0.47) | C5AR1CXCR3 | |
| SCHEMBL1912900 | 0.91 | C5AR1 (0.46) | C5AR1CXCR3 | |
| SCHEMBL1912902 | 0.91 | C5AR1 (0.46) | C5AR1CXCR3 | |
| SCHEMBL5134524 | 0.91 | C5AR1 (0.46) | C5AR1CXCR3 | |
| SCHEMBL1912909 | 0.89 | C5AR1 (0.61) | C5AR1CXCR3 | |
| SCHEMBL648047 | 0.89 | C5AR1 (0.61) | C5AR1CXCR3 | |
| SCHEMBL1912912 | 0.86 | C5AR1 (0.62) | C5AR1 | |
| SCHEMBL651559 | 0.86 | C5AR1 (0.62) | C5AR1 | |
| SCHEMBL1912913 | 0.82 | C5AR1 (0.40) | C5AR1CXCR3 | |
| SCHEMBL650465 | 0.82 | C5AR1 (0.40) | C5AR1CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119665-B2 | Aryl imidazoles and related compounds as C5a receptor modulators | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2012-02-21 | — | — | US | disclosed |
| US-8119665-B2 | Aryl imidazoles and related compounds as C5a receptor modulators | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2012-02-21 | — | — | US | disclosed |
| US-8119665-B2 | Aryl imidazoles and related compounds as C5a receptor modulators | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2012-02-21 | — | — | US | disclosed |
| US-7186734-B2 | Aryl imidazoles and related compounds as C5a receptor modulators | NEUROGEN CORPORATION (US) | 2007-03-06 | — | — | US | disclosed |
| US-7186734-B2 | Aryl imidazoles and related compounds as C5a receptor modulators | NEUROGEN CORPORATION (US) | 2007-03-06 | — | — | US | disclosed |
| US-7186734-B2 | Aryl imidazoles and related compounds as C5a receptor modulators | NEUROGEN CORPORATION (US) | 2007-03-06 | — | — | US | disclosed |