SCHEMBL6480867

SCHEMBL6480867

O=C1CCCC(=O)C1C(=O)c1ccc(Cl)c(OCCn2cnnn2)c1Cl

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.37
KMT2A Q03164 1/20 0.33
TP53 P04637 3/20 0.31
TACR2 P21452 1/20 0.31
TACR1 P25103 1/20 0.31
HPD P32754 1/20 0.31
HTR4 Q13639 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6479779 0.87 MAPK1 (0.33) MAPK1KMT2ATP53MAPT
SCHEMBL6480302 0.85 MAPK1 (0.35) MAPK1KMT2ATP53HTR4
SCHEMBL6480542 0.85 KMT2A (0.34) MAPK1KMT2ATP53MAPT
SCHEMBL6481157 0.82 POLB (0.33) HPD
SCHEMBL6493708 0.82 MAPK1 (0.33) MAPK1KMT2ATP53MAPT
SCHEMBL587431 0.82 MAPK1 (0.43) MAPK1KMT2ATP53MAPT
SCHEMBL587146 0.82 MAPK1 (0.43) MAPK1KMT2ATP53MAPT
SCHEMBL6481403 0.82 MAPK1 (0.35) MAPK1TP53HPD
SCHEMBL6480901 0.81 MAPK1 (0.35) MAPK1KMT2ATP53MAPT
SCHEMBL6480971 0.80 MAPK1 (0.35) MAPK1KMT2AHPD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050090398-A1 Novel tetrazole derivative useful as herbicides YANAGI AKIHIKO (JP) 2005-04-28 US disclosed
EP-1476437-A1 NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES Bayer CropScience AG (DE) 2004-11-17 EP disclosed
WO-2003066607-A1 NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2003-08-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050090398-A1 Novel tetrazole derivative useful as herbicides DDT, TTI1, CYP1A1 MAPK1 2914/4885KMT2A 1800/4885TP53 1908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.