SCHEMBL6479779

SCHEMBL6479779

CS(=O)(=O)c1ccc(C(=O)C2C(=O)CCCC2=O)c(Cl)c1OCCn1cnnn1

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.33
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HTT P42858 1/20 0.32
TP53 P04637 2/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6480542 0.98 KMT2A (0.34) MAPK1KMT2AALDH1A1HTTTP53
SCHEMBL6480867 0.87 MAPK1 (0.37) MAPK1KMT2ATP53MAPT
SCHEMBL6480268 0.84 ALDH1A1 (0.30) MAPK1ALDH1A1HTT
SCHEMBL6480998 0.84 TP53 (0.36) MAPK1KMT2AALDH1A1TP53MAPT
SCHEMBL6489720 0.84 TP53 (0.35) MAPK1TP53MAPT
SCHEMBL6480955 0.83 ALDH1A1 (0.31) MAPK1ALDH1A1HTT
SCHEMBL6450192 0.83 ALDH1A1 (0.30) MAPK1ALDH1A1HTT
SCHEMBL6482095 0.83 LMNA (0.33) KMT2AALDH1A1
SCHEMBL6491617 0.83 TP53 (0.32) MAPK1ALDH1A1HTTTP53MAPT
SCHEMBL6483175 0.82 KMT2A (0.33) KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016195384-A1 BENZOYL CYCLOHEXANEDIONE COMPOUND, AND HERBICIDE CONTAINING SAME 한국화학연구원 2016-12-08 WO disclosed
US-20050090398-A1 Novel tetrazole derivative useful as herbicides YANAGI AKIHIKO (JP) 2005-04-28 US disclosed
EP-1476437-A1 NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES Bayer CropScience AG (DE) 2004-11-17 EP disclosed
WO-2003066607-A1 NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2003-08-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050090398-A1 Novel tetrazole derivative useful as herbicides DDT, TTI1, CYP1A1 MAPK1 2914/4885KMT2A 1800/4885ALDH1A1 533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.