Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | UBE2M | P61081 | 1/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6480678 | 0.96 | ACKR3 (0.44) | RORCACKR3MAPTKMT2AMEN1 | |
| SCHEMBL6480480 | 0.96 | RORC (0.43) | RORCACKR3MAPTKMT2AMEN1 | |
| SCHEMBL6492171 | 0.95 | ACKR3 (0.46) | RORCACKR3MAPTKMT2AMEN1 | |
| SCHEMBL6489116 | 0.91 | HSD17B10 (0.44) | MAPTKMT2AMEN1HSD17B10USP2 | |
| SCHEMBL6480758 | 0.90 | PARP1 (0.42) | RORCACKR3MAPTKMT2AMEN1 | |
| SCHEMBL6490688 | 0.87 | MGLL (0.44) | RORCMAPTKMT2AMEN1HSD17B10 | |
| SCHEMBL6480722 | 0.87 | NPSR1 (0.49) | ALDH1A1HSD17B10KDM4ELMNASMN1; SMN2 | |
| SCHEMBL6480771 | 0.87 | NPSR1 (0.46) | MAPTALDH1A1HSD17B10POLBKDM4E | |
| SCHEMBL6492402 | 0.84 | NPSR1 (0.46) | ALDH1A1TSHRSMN1; SMN2MALT1 | |
| SCHEMBL6489974 | 0.84 | JAK2 (0.43) | MAPTKMT2AHSD17B10SMN1; SMN2MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050215614-A1 | Substituted indoles and their use as hcv inhibitors | RIGEL PHARMACEUTICALS, INC. (US) | 2005-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215614-A1 | Substituted indoles and their use as hcv inhibitors | IDO1, IDO2, HAVCR2 | RORC 387/4885ACKR3 895/4885MAPT 3587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.