Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6481048 | 1.00 | LMNA (0.54) | LMNAKMT2ATDP1MEN1THRB | |
| SCHEMBL6481144 | 0.96 | LMNA (0.59) | LMNAKMT2ATDP1MEN1THRB | |
| SCHEMBL6481141 | 0.96 | LMNA (0.59) | LMNAKMT2ATDP1MEN1THRB | |
| SCHEMBL547777 | 0.84 | TDP1 (0.52) | LMNAKMT2ATDP1MEN1THRB | |
| SCHEMBL986911 | 0.84 | TDP1 (0.52) | LMNAKMT2ATDP1MEN1THRB | |
| SCHEMBL30402244 | 0.84 | TDP1 (0.52) | LMNAKMT2ATDP1MEN1THRB | |
| SCHEMBL29364404 | 0.79 | LMNA (0.58) | LMNAKMT2ATDP1MEN1THRB | |
| SCHEMBL652955 | 0.79 | LMNA (0.58) | LMNAKMT2ATDP1MEN1THRB | |
| SCHEMBL6494054 | 0.75 | RAB9A (0.46) | LMNAKMT2ATDP1MEN1BLM | |
| SCHEMBL10466277 | 0.75 | TRIM24 (0.50) | LMNAKMT2ATDP1MEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050096491-A1 | Aromatic methylidene compound, methylstyryl compound for producing the same, production method therefor, and organic electroluminescent element | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2005-05-05 | — | — | US | disclosed |
| US-20030224206-A1 | Aromatic methylidene compound, methylstyryl compound for producing the same, production method therefor, and organic electroluminescent element | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. | 2003-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050096491-A1 | Aromatic methylidene compound, methylstyryl compound for producing the same, production method therefor, and organic electroluminescent element | OR51E2, CYP4F11, ACAD11 | LMNA 3310/4885KMT2A 1302/4885TDP1 3119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.