Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 2/20 | 0.30 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL647955 | 0.86 | MEN1 (0.36) | MEN1KMT2A | |
| SCHEMBL647954 | 0.81 | KMT2A (0.34) | MEN1KMT2A | |
| SCHEMBL652070 | 0.77 | MEN1 (0.37) | MEN1KMT2A | |
| SCHEMBL650005 | 0.73 | MEN1 (0.39) | MEN1KMT2A | |
| SCHEMBL648038 | 0.71 | KMT2A (0.36) | MEN1KMT2A | |
| SCHEMBL649017 | 0.70 | SLC6A4 (0.33) | — | |
| SCHEMBL648912 | 0.68 | KMT2A (0.37) | MEN1KMT2AMMEAGTR1 | |
| SCHEMBL648563 | 0.68 | MEN1 (0.36) | MEN1KMT2AAGTR1 | |
| SCHEMBL651017 | 0.67 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL648905 | 0.66 | RARA (0.35) | MEN1KMT2AMMEAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119665-B2 | Aryl imidazoles and related compounds as C5a receptor modulators | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2012-02-21 | — | — | US | disclosed |