Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 20/20 | 0.67 |
| ▸ | KDR | P35968 | 11/20 | 0.54 |
| ▸ | CSK | P41240 | 4/20 | 0.52 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.52 |
| ▸ | TEK | Q02763 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | LCK | P06239 | 2/20 | 0.51 |
| ▸ | YES1 | P07947 | 2/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.51 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.47 |
| ▸ | GAK | O14976 | 1/20 | 0.47 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.47 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.47 |
| ▸ | STK10 | O94804 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | LYN | P07948 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3279959 | 0.81 | SRC (0.84) | SRCKDRCSKEPHB4EGFR | |
| SCHEMBL3275761 | 0.80 | SRC (1.00) | SRCKDRCSKEPHB4TEK | |
| SCHEMBL3278858 | 0.79 | SRC (0.66) | SRCKDRCSKEPHB4TEK | |
| SCHEMBL18533999 | 0.79 | SRC (0.79) | SRCKDRCSKEPHB4EGFR | |
| Hydrochloric Acid SCHEMBL3280091 | 0.78 | SRC (0.98) | SRCKDRCSKEPHB4TEK | |
| Hydrochloric Acid SCHEMBL3283164 | 0.78 | SRC (0.65) | SRCKDRCSKEPHB4TEK | |
| SCHEMBL3195521 | 0.78 | SRC (0.78) | SRCKDRCSKEPHB4EGFR | |
| Hydrochloric Acid SCHEMBL3276006 | 0.78 | SRC (0.77) | SRCKDRCSKEPHB4EGFR | |
| Hydrochloric Acid SCHEMBL3281883 | 0.76 | SRC (0.78) | SRCKDRCSKEPHB4TEK | |
| Hydrochloric Acid SCHEMBL6736242 | 0.75 | SRC (0.63) | SRCKDRCSKEPHB4TEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038050-A1 | Quinazoline derivatives for the treatment of t cell mediated diseases | ASTRAZENECA AB (SE) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038050-A1 | Quinazoline derivatives for the treatment of t cell mediated diseases | CD4, HLA-DRB1, IFNG | SRC 3241/4885KDR 4015/4885CSK 745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.