Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4421840 | 1.00 | ALDH1A1 (0.50) | ALDH1A1THRBLMNASMN1; SMN2CASP1 | |
| SCHEMBL6735652 | 0.91 | ALDH1A1 (0.46) | ALDH1A1THRBLMNASMN1; SMN2CASP1 | |
| SCHEMBL4435142 | 0.90 | MBTPS1 (0.47) | ALDH1A1THRBLMNASMN1; SMN2CASP1 | |
| SCHEMBL4435139 | 0.90 | MBTPS1 (0.47) | ALDH1A1THRBLMNASMN1; SMN2CASP1 | |
| SCHEMBL6735648 | 0.89 | ALDH1A1 (0.42) | ALDH1A1THRBLMNASMN1; SMN2CASP1 | |
| SCHEMBL6735653 | 0.89 | ALDH1A1 (0.42) | ALDH1A1THRBLMNASMN1; SMN2CASP1 | |
| SCHEMBL4425138 | 0.89 | ALDH1A1 (0.53) | ALDH1A1THRBLMNASMN1; SMN2POLB | |
| SCHEMBL6481137 | 0.89 | ALDH1A1 (0.53) | ALDH1A1THRBLMNASMN1; SMN2POLB | |
| SCHEMBL6475048 | 0.87 | ALDH1A1 (0.47) | ALDH1A1THRBLMNASMN1; SMN2LPAR1 | |
| SCHEMBL4433880 | 0.87 | ALDH1A1 (0.47) | ALDH1A1THRBLMNASMN1; SMN2LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6939888-B2 | 1-H-3-arylpirrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2005-09-06 | — | — | US | disclosed |
| US-6472419-B1 | 1-H-3-aryl-pyrrolidine-2, 4-dione derivatives as pest-control agents | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | disclosed |