SCHEMBL648231

SCHEMBL648231

CCCCCNc1ccccc1C(N)=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 4/20 0.55
CNR1 P21554 1/20 0.52
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
NR1I2 O75469 1/20 0.51
LMNA P02545 1/20 0.51
CHRM2 P08172 1/20 0.51
CYP3A4 P08684 1/20 0.51
ADRA2A P08913 1/20 0.51
MAPT P10636 1/20 0.51
OPRK1 P41145 1/20 0.51
HTR2B P41595 1/20 0.51
SLC6A3 Q01959 1/20 0.51
HDAC6 Q9UBN7 1/20 0.51
PLK1 P53350 1/20 0.51
AGTR1 P30556 2/20 0.48
NAAA Q02083 1/20 0.48
TSHR P16473 1/20 0.47
HTT P42858 1/20 0.47
HPGD P15428 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7590166 0.98 CNR2 (0.56) CNR2CNR1MEN1KMT2ANR1I2
SCHEMBL14577687 0.95 TSHR (0.53) CNR2CNR1MEN1KMT2ANR1I2
SCHEMBL5392212 0.88 KDM4E (0.58) MEN1KMT2APLK1AGTR1HPGD
SCHEMBL1825731 0.86 CNR2 (0.49) CNR2CNR1MEN1KMT2ANR1I2
SCHEMBL2731963 0.86 CNR2 (0.52) CNR2CNR1MEN1KMT2ANR1I2
SCHEMBL466141 0.85 PLK1 (0.63) CNR2CNR1PLK1AGTR1HPGD
SCHEMBL6532561 0.85 CNR2 (0.56) CNR2CNR1PLK1NAAATSHR
SCHEMBL11443814 0.84 PLK1 (0.66) CNR2CNR1PLK1AGTR1NAAA
SCHEMBL5272720 0.84 PLK1 (0.66) CNR2CNR1PLK1AGTR1NAAA
SCHEMBL3475665 0.84 PLK1 (0.66) CNR2CNR1PLK1AGTR1NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116535357-A Arylamino benzamide derivative containing substituted pyrazole structure, preparation method and application 西北农林科技大学 2023-08-04 CN claimed
CN-104736148-B Parazoon expeling composition and the expelling method of parazoon 三井化学AGRO株式会社 2018-01-12 CN claimed
EP-0855387-A1 2-ACYLAMINOBENZAMIDE DERIVATIVES AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY THE SUPERMULTIPLICATION OF VASCULAR INTIMAL CELLS KISSEI PHARMACEUTICAL CO., LTD. (JP) 1998-07-29 EP claimed
EP-0657418-A1 Acylamino-benzamides and fungicides containing them BASF AKTIENGESELLSCHAFT (DE) 1995-06-14 EP claimed
JP-5155837-A None JP disclosed
JP-5155837-A None JP disclosed
JP-10330254-A None JP disclosed
JP-5201944-A None JP disclosed
JP-10259129-A None JP disclosed
JP-10306024-A None JP disclosed
US-20230355590-A1 ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE NISSAN CHEMICAL CORPORATION (JP) 2023-11-09 US disclosed
CN-116535357-A Arylamino benzamide derivative containing substituted pyrazole structure, preparation method and application 西北农林科技大学 2023-08-04 CN disclosed
EP-0468682-A1 Fungicidal acylaminbezamides, their production and use ZENECA LIMITED (GB) 1992-01-29 EP disclosed
EP-0468682-A1 Fungicidal acylaminbezamides, their production and use ZENECA LIMITED (GB) 1992-01-29 EP disclosed
US-4999381-A Fungicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-03-12 US disclosed
EP-0381330-A1 Fungicides ZENECA LIMITED (GB) 1990-08-08 EP disclosed
US-4581177-A Process for the preparation of 3-cyano-4-aminoacetophenones DR. KARL THOMAE GMBH (DE) 1986-04-08 US disclosed
US-4522945-A SEROTONINE ANTAGONISTS JANSSEN PHARMACEUTICA N.V. (BE) 1985-06-11 US disclosed
EP-0013612-B1 (PIPERIDINYLALKYL)QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM JANSSEN PHARMACEUTICA N.V. (BE) 1983-11-09 EP disclosed
US-4335127-A POTENT SEROTONIN ANTAGONISTS JANSSEN PHARMACEUTICA, N.V. (BE) 1982-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230355590-A1 ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE HDAC7, ACHE, BRDT CNR2 2915/4885CNR1 3775/4885MEN1 3896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.