Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 16/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 16/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 16/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3044718 | 0.99 | ADORA2A (0.54) | ADORA2AADORA2BADORA1DUSP3CHRM4 | |
| SCHEMBL6476220 | 0.93 | ADORA2A (0.51) | ADORA2AADORA2BADORA1DUSP3CHRM4 | |
| Hydrochloric Acid SCHEMBL3048459 | 0.92 | ADORA2A (0.51) | ADORA2AADORA2BADORA1DUSP3CHRM4 | |
| SCHEMBL6486465 | 0.91 | ADORA2B (0.54) | ADORA2AADORA2BADORA1DUSP3CHRM4 | |
| Hydrochloric Acid SCHEMBL3059825 | 0.90 | ADORA2B (0.53) | ADORA2AADORA2BADORA1DUSP3CHRM4 | |
| SCHEMBL6481259 | 0.90 | ADORA2B (0.53) | ADORA2AADORA2BADORA1DUSP3CHRM4 | |
| Hydrochloric Acid SCHEMBL3048033 | 0.89 | ADORA2B (0.53) | ADORA2AADORA2BADORA1DUSP3CHRM4 | |
| SCHEMBL3053634 | 0.89 | DUSP3 (0.54) | ADORA2AADORA2BADORA1DUSP3CHRM4 | |
| SCHEMBL3046423 | 0.88 | DUSP3 (0.56) | ADORA2AADORA2BADORA1DUSP3CHRM4 | |
| SCHEMBL7198817 | 0.88 | ADORA2A (0.51) | ADORA2AADORA2BADORA1DUSP3CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6963000-B2 | Benzothiazole derivatives with activity as adenosine receptor ligands | HOFFMAN-LA ROCHE INC. (US) | 2005-11-08 | — | — | US | claimed |