Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 15/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 14/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 14/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3059825 | 0.99 | ADORA2B (0.53) | ADORA2BADORA2AADORA1DUSP3LMNA | |
| SCHEMBL6481259 | 0.93 | ADORA2B (0.53) | ADORA2BADORA2AADORA1DUSP3LMNA | |
| Hydrochloric Acid SCHEMBL3048033 | 0.93 | ADORA2B (0.53) | ADORA2BADORA2AADORA1DUSP3LMNA | |
| SCHEMBL6482952 | 0.91 | ADORA2A (0.55) | ADORA2BADORA2AADORA1DUSP3LMNA | |
| SCHEMBL3046423 | 0.90 | DUSP3 (0.56) | ADORA2BADORA2AADORA1DUSP3LMNA | |
| SCHEMBL6483836 | 0.90 | ADORA2B (0.53) | ADORA2BADORA2AADORA1DUSP3LMNA | |
| Hydrochloric Acid SCHEMBL3044718 | 0.90 | ADORA2A (0.54) | ADORA2BADORA2AADORA1DUSP3LMNA | |
| SCHEMBL6476606 | 0.89 | ADORA2B (0.50) | ADORA2BADORA2AADORA1DUSP3LMNA | |
| Hydrochloric Acid SCHEMBL3043464 | 0.89 | ADORA2B (0.52) | ADORA2BADORA2AADORA1DUSP3LMNA | |
| SCHEMBL6476220 | 0.89 | ADORA2A (0.51) | ADORA2BADORA2AADORA1DUSP3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6963000-B2 | Benzothiazole derivatives with activity as adenosine receptor ligands | HOFFMAN-LA ROCHE INC. (US) | 2005-11-08 | — | — | US | claimed |