SCHEMBL6483276

SCHEMBL6483276

C=C(C)C(=O)OC(CC)[Si](C(C)OC)(C(C)OC)C(C)OC

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
ALDH1A1 P00352 1/20 0.36
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4943466 0.84 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL80262 0.78 TSHR (0.36) TSHRALDH1A1THRB
SCHEMBL17801655 0.77 ALDH1A1 (0.40) TSHRALDH1A1THRB
SCHEMBL6575777 0.77 ALDH1A1 (0.40) TSHRALDH1A1THRB
SCHEMBL25561 0.77 ALDH1A1 (0.40) TSHRALDH1A1THRB
SCHEMBL5826669 0.77 ALDH1A1 (0.40) TSHRALDH1A1THRB
SCHEMBL2009455 0.77 TSHR (0.39) TSHRALDH1A1THRB
SCHEMBL1677860 0.77 TSHR (0.39) TSHRALDH1A1THRB
SCHEMBL3808301 0.76 ALDH1A1 (0.39) TSHRALDH1A1THRB
SCHEMBL1512952 0.76 ALDH1A1 (0.39) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050170282-A1 Lithographic printing plate precursor and lithographic printing method FUJI PHOTO FILM CO., LTD. 2005-08-04 US disclosed