Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.65 |
| ▸ | MME | P08473 | 1/20 | 0.64 |
| ▸ | ACE | P12821 | 1/20 | 0.64 |
| ▸ | CPA1 | P15085 | 1/20 | 0.64 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.64 |
| ▸ | GPR34 | Q9UPC5 | 4/20 | 0.60 |
| ▸ | PPARA | Q07869 | 4/20 | 0.58 |
| ▸ | PPARD | Q03181 | 1/20 | 0.58 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413779 | 0.88 | PPARG (0.62) | PPARGMMEACECPA1ACE2 | |
| SCHEMBL6034466 | 0.88 | PPARG (0.62) | PPARGMMEACECPA1ACE2 | |
| SCHEMBL6034470 | 0.88 | PPARG (0.62) | PPARGMMEACECPA1ACE2 | |
| SCHEMBL8413776 | 0.88 | PPARG (0.62) | PPARGMMEACECPA1ACE2 | |
| SCHEMBL1855602 | 0.88 | PPARG (0.62) | PPARGMMEACECPA1ACE2 | |
| SCHEMBL2035189 | 0.86 | PPARG (0.67) | PPARGMMEACECPA1ACE2 | |
| SCHEMBL2030203 | 0.86 | PPARG (0.67) | PPARGMMEACECPA1ACE2 | |
| SCHEMBL8760872 | 0.86 | PPARG (0.67) | PPARGMMEACECPA1ACE2 | |
| SCHEMBL839840 | 0.85 | SIGMAR1 (0.56) | MMEACECPA1ACE2 | |
| SCHEMBL7271174 | 0.85 | SIGMAR1 (0.56) | MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916812-B2 | Dietetic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-07-12 | — | — | US | disclosed |
| US-20030232807-A1 | Alpha-aminoamide derivatives as melanocortin agonists | POINDEXTER GRAHAM S (US) | 2003-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232807-A1 | Alpha-aminoamide derivatives as melanocortin agonists | MC1R, MC5R, MC4R | PPARG 528/4885MME 438/4885ACE 2562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.