Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.67 |
| ▸ | MTOR | P42345 | 1/20 | 0.67 |
| ▸ | ADK | P55263 | 1/20 | 0.67 |
| ▸ | VCP | P55072 | 2/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.44 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PAK4 | O96013 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3644191 | 0.87 | NISCH (0.74) | NISCHMTORADKVCPSCN9A | |
| SCHEMBL16777437 | 0.87 | NISCH (0.72) | NISCHMTORADKVCPSCN9A | |
| SCHEMBL471923 | 0.85 | NISCH (0.70) | NISCHMTORADKVCPSCN9A | |
| SCHEMBL2198284 | 0.83 | NISCH (0.67) | NISCHMTORADKVCPCSNK1A1 | |
| 2-Phenylimidazole SCHEMBL9719773 | 0.81 | NISCH (1.00) | NISCHMTORADKVCPCSNK1A1 | |
| 2-Phenylimidazole SCHEMBL8901 | 0.81 | NISCH (1.00) | NISCHMTORADKVCPCSNK1A1 | |
| 2-Phenylimidazole SCHEMBL1954238 | 0.79 | NISCH (0.95) | NISCHMTORADKVCPCSNK1A1 | |
| 2-Phenylimidazole SCHEMBL11072040 | 0.79 | NISCH (0.95) | NISCHMTORADKVCPCSNK1A1 | |
| 2-Phenylimidazole SCHEMBL8898735 | 0.79 | NISCH (0.95) | NISCHMTORADKVCPCSNK1A1 | |
| 2-Phenylimidazole SCHEMBL5796856 | 0.79 | NISCH (0.95) | NISCHMTORADKVCPCSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1582516-A1 | NITROGENOUS HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2005-10-05 | — | — | EP | disclosed |