2-Phenylimidazole

2-Phenylimidazole

SCHEMBL5796856

[Ir].c1ccc(-c2ncc[nH]2)cc1

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 2/20 0.95
MTOR P42345 1/20 0.95
ADK P55263 1/20 0.95
ALDH1A1 P00352 3/20 0.58
KDM4E B2RXH2 2/20 0.58
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP19A1 P11511 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
PDE3B Q13370 1/20 0.47
PDE3A Q14432 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
CSNK1A1 P48729 2/20 0.44
TYRO3 Q06418 2/20 0.44
DYRK1B Q9Y463 2/20 0.44
VCP P55072 1/20 0.44
ADRA2A P08913 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Phenylimidazole SCHEMBL9719773 0.98 NISCH (1.00) NISCHMTORADKALDH1A1KDM4E
2-Phenylimidazole SCHEMBL8901 0.98 NISCH (1.00) NISCHMTORADKALDH1A1KDM4E
2-Phenylimidazole SCHEMBL11072040 0.95 NISCH (0.95) NISCHMTORADKALDH1A1KDM4E
Biphenyl SCHEMBL7409338 0.95 NISCH (0.95) NISCHMTORADKALDH1A1KDM4E
2-Phenylimidazole SCHEMBL28193283 0.95 NISCH (0.95) NISCHMTORADKALDH1A1KDM4E
2-Phenylimidazole SCHEMBL1954238 0.95 NISCH (0.95) NISCHMTORADKALDH1A1KDM4E
2-Phenylimidazole SCHEMBL8898735 0.95 NISCH (0.95) NISCHMTORADKALDH1A1KDM4E
2-Phenylimidazole SCHEMBL1881537 0.95 NISCH (0.95) NISCHMTORADKALDH1A1KDM4E
2-Phenylimidazole SCHEMBL31511436 0.95 NISCH (0.95) NISCHMTORADKALDH1A1KDM4E
2-Phenylimidazole SCHEMBL28283863 0.95 NISCH (0.95) NISCHMTORADKALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10978648-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-04-13 US disclosed
CN-106588998-B Heteroleptic iridium carbene complex and light-emitting device using same 环球展览公司 2020-07-17 CN disclosed
US-20180019414-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-01-18 US disclosed
US-9847495-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-12-19 US disclosed
US-9812656-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-11-07 US disclosed
CN-106588998-A Heteroleptic iridium carbene complexes and light emitting device using them 环球展览公司 2017-04-26 CN disclosed
CN-103596967-B Heteroleptic iridium carbene complex and light-emitting device using same 环球展览公司 2016-12-21 CN disclosed
US-20140131687-A1 HETEROLEPTIC IRIDIUM CARBENE COMPLEXES AND LIGHT EMITTING DEVICE USING THEM UNIVERSAL DISPLAY CORPORATION (US) 2014-05-15 US disclosed
US-20140110691-A1 HETEROLEPTIC IRIDIUM CARBENE COMPLEXES AND LIGHT EMITTING DEVICE USING THEM UNIVERSAL DISPLAY CORPORATION (US) 2014-04-24 US disclosed
CN-103596967-A Heteroleptic iridium carbene complex and light-emitting device using same UNIVERSAL DISPLAY CORP 2014-02-19 CN disclosed
WO-2012170571-A1 HETEROLEPTIC IRIDIUM CARBENE COMPLEXES AND LIGHT EMITTING DEVICE USING THEM UNIVERSAL DISPLAY CORPORATION (US) 2012-12-13 WO disclosed
WO-2012170463-A1 HETEROLEPTIC IRIDIUM CARBENE COMPLEXES AND LIGHT EMITTING DEVICE USING THEM UNIVERSAL DISPLAY CORPORATION (US) 2012-12-13 WO disclosed
WO-2006046980-A1 ORGANIC LIGHT EMITTING MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2006-05-04 WO disclosed
US-20060008670-A1 Organic light emitting materials and devices UNIVERSAL DISPLAY CORPORATION 2006-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180019414-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, ICOSLG, OCIAD1 NISCH 716/4885MTOR 695/4885ADK 2346/4885
US-20060008670-A1 Organic light emitting materials and devices PPOX, CLTB, TPMT NISCH 1019/4885MTOR 3650/4885ADK 2776/4885
US-10978648-B2 Organic electroluminescent materials and devices OCIAD2, ICOSLG, OCIAD1 NISCH 716/4885MTOR 695/4885ADK 2346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.