Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of 2-Phenylimidazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.44 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.95 |
| ▸ | MTOR | P42345 | 1/20 | 0.95 |
| ▸ | ADK | P55263 | 1/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.44 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.44 |
| ▸ | VCP | P55072 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Phenylimidazole SCHEMBL8901 | 0.98 | NISCH (1.00) | NISCHMTORADKALDH1A1KDM4E | |
| 2-Phenylimidazole SCHEMBL9719773 | 0.98 | NISCH (1.00) | NISCHMTORADKALDH1A1KDM4E | |
| 2-Phenylimidazole SCHEMBL5796856 | 0.95 | NISCH (0.95) | NISCHMTORADKALDH1A1KDM4E | |
| Biphenyl SCHEMBL7409338 | 0.95 | NISCH (0.95) | NISCHMTORADKALDH1A1KDM4E | |
| 2-Phenylimidazole SCHEMBL28283863 | 0.95 | NISCH (0.95) | NISCHMTORADKALDH1A1KDM4E | |
| 2-Phenylimidazole SCHEMBL8898735 | 0.95 | NISCH (0.95) | NISCHMTORADKALDH1A1KDM4E | |
| 2-Phenylimidazole SCHEMBL1881537 | 0.95 | NISCH (0.95) | NISCHMTORADKALDH1A1KDM4E | |
| 2-Phenylimidazole SCHEMBL31511436 | 0.95 | NISCH (0.95) | NISCHMTORADKALDH1A1KDM4E | |
| 2-Phenylimidazole SCHEMBL11072040 | 0.95 | NISCH (0.95) | NISCHMTORADKALDH1A1KDM4E | |
| 2-Phenylimidazole SCHEMBL28193283 | 0.95 | NISCH (0.95) | NISCHMTORADKALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116140857-A | Low-temperature soldering paste for reflow soldering and preparation method and application thereof | 深圳市汉尔信电子科技有限公司 | 2023-05-23 | — | — | CN | claimed |
| US-12605794-B2 | Flux and solder paste | SENJU METAL INDUSTRY CO., LTD. (JP) | 2026-04-21 | — | — | US | disclosed |
| US-12515281-B2 | Flux | SENJU METAL INDUSTRY CO., LTD. (JP) | 2026-01-06 | — | — | US | disclosed |
| EP-4332257-B1 | FLUX AND SOLDER PASTE | SENJU METAL INDUSTRY CO (JP) | 2025-10-15 | — | — | EP | disclosed |
| US-12365054-B2 | Flux and solder paste | SENJU METAL INDUSTRY CO., LTD. | 2025-07-22 | — | — | US | disclosed |
| US-12304008-B2 | Flux and method for producing assembly | SENJU METAL INDUSTRY CO., LTD. (JP) | 2025-05-20 | — | — | US | disclosed |
| US-12269806-B2 | Flux and solder paste | SENJU METAL INDUSTRY CO., LTD. (JP) | 2025-04-08 | — | — | US | disclosed |
| CN-118176084-B | Soldering flux and method for producing bonded body | 千住金属工业株式会社 | 2025-03-18 | — | — | CN | disclosed |
| CN-119585073-A | Soldering flux and soldering paste | 千住金属工业株式会社 | 2025-03-07 | — | — | CN | disclosed |
| CN-118354863-B | Method for producing soldering flux and bonded body | 千住金属工业株式会社 | 2025-02-25 | — | — | CN | disclosed |
| US-20190030656-A1 | Flux | SENJU METAL INDUSTRY CO., LTD. (JP) | 2019-01-31 | — | — | US | disclosed |
| CN-109071954-A | Curable composition, cured film using same, and overcoat film | 昭和电工株式会社 | 2018-12-21 | — | — | CN | disclosed |
| EP-3409412-A1 | FLUX | Senju Metal Industry Co., Ltd (JP) | 2018-12-05 | — | — | EP | disclosed |
| CN-108472771-A | soldering flux | 千住金属工业株式会社 | 2018-08-31 | — | — | CN | disclosed |
| CN-102482269-B | Proline derivatives | NATIONAL HEALTH RESEARCH INSTITUTES (CN) | 2015-07-29 | — | — | CN | disclosed |
| US-8415482-B2 | Proline derivatives | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2013-04-09 | — | — | US | disclosed |
| EP-2507232-A2 | PROLINE DERIVATIVES | National Health Research Institutes (TW) | 2012-10-10 | — | — | EP | disclosed |
| CN-102482269-A | Proline derivatives | NAT HEALTH RESEARCH INSTITUTES | 2012-05-30 | — | — | CN | disclosed |
| US-20110136799-A1 | PROLINE DERIVATIVES | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2011-06-09 | — | — | US | disclosed |
| WO-2011068941-A2 | PROLINE DERIVATIVES | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2011-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136799-A1 | PROLINE DERIVATIVES | PNISR, ARGLU1, PRR12 | ADRA2A 4149/4885NISCH 3342/4885MTOR 3282/4885 |
| US-12269806-B2 | Flux and solder paste | OTC, SLC25A11, PROC | ADRA2A 4786/4885NISCH 455/4885MTOR 2691/4885 |
| US-12605794-B2 | Flux and solder paste | RIOK2, TRA2B, BAG2 | ADRA2A 911/4885NISCH 1857/4885MTOR 1109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.