Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 7/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | NR2E1 | Q9Y466 | 5/20 | 0.73 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.64 |
| ▸ | HTR2B | P41595 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.64 |
| ▸ | HTR2A | P28223 | 3/20 | 0.64 |
| ▸ | HTR2C | P28335 | 3/20 | 0.64 |
| ▸ | HTR6 | P50406 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | SCN1A | P35498 | 2/20 | 0.64 |
| ▸ | SLC10A1 | Q14973 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6483890 | 1.00 | CYP1A2 (1.00) | CYP1A2KDM4ECYP2C19MEN1KMT2A | |
| SCHEMBL8566653 | 1.00 | CYP1A2 (1.00) | CYP1A2KDM4ECYP2C19MEN1KMT2A | |
| SCHEMBL29437209 | 1.00 | CYP1A2 (1.00) | CYP1A2KDM4ECYP2C19MEN1KMT2A | |
| SCHEMBL1394219 | 0.91 | CYP1A2 (0.83) | CYP1A2KDM4ECYP2C19MEN1KMT2A | |
| SCHEMBL29437208 | 0.91 | CYP1A2 (0.83) | CYP1A2KDM4ECYP2C19MEN1KMT2A | |
| SCHEMBL27902830 | 0.85 | CYP1A2 (0.74) | CYP1A2KDM4ECYP2C19MEN1KMT2A | |
| SCHEMBL773269 | 0.85 | NR2E1 (1.00) | CYP1A2KDM4ECYP2C19MEN1KMT2A | |
| SCHEMBL8539878 | 0.85 | CYP1A2 (0.73) | CYP1A2KDM4ECYP2C19MEN1KMT2A | |
| SCHEMBL9777763 | 0.85 | NR2E1 (1.00) | CYP1A2KDM4ECYP2C19MEN1KMT2A | |
| SCHEMBL9777869 | 0.85 | NR2E1 (1.00) | CYP1A2KDM4ECYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005003140-A1 | 4-OXO-4,7-DIHYDROTHIENO[2,3-B]PYRIDINE-5-CARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-01-13 | — | — | WO | disclosed |
| US-20050004161-A1 | 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides as antiviral agents | AGOURON PHARMACEUTICALS, INC. | 2005-01-06 | — | — | US | disclosed |
| US-5208333-A | (2R)-1-(ARYLOXY)-3-(BUTYRYLOXY)-2-PROPANOLS | BASF AKTIENGESELLSCHAFT (DE) | 1993-05-04 | — | — | US | disclosed |
| EP-0320726-A2 | (2R)-aryloxyl-3-n-butyryloxy-propan-2-ols | BASF Aktiengesellschaft (DE) | 1989-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004161-A1 | 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides as antiviral agents | ZC3HAV1, IRF3, BRD4 | CYP1A2 1382/4885KDM4E 40/4885CYP2C19 2078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.