Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E1 | Q9Y466 | 5/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.73 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.62 |
| ▸ | HTR2B | P41595 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.62 |
| ▸ | HTR2A | P28223 | 3/20 | 0.62 |
| ▸ | HTR2C | P28335 | 3/20 | 0.62 |
| ▸ | HTR6 | P50406 | 3/20 | 0.62 |
| ▸ | HTR1B | P28222 | 3/20 | 0.62 |
| ▸ | SCN1A | P35498 | 2/20 | 0.62 |
| ▸ | SLC10A1 | Q14973 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9777869 | 1.00 | NR2E1 (1.00) | NR2E1CYP1A2MEN1KMT2ACYP2C19 | |
| SCHEMBL9777763 | 1.00 | NR2E1 (1.00) | NR2E1CYP1A2MEN1KMT2ACYP2C19 | |
| Hydrochloric Acid SCHEMBL31396673 | 0.98 | NR2E1 (0.97) | NR2E1CYP1A2MEN1KMT2ACYP2C19 | |
| Hydrochloric Acid SCHEMBL2460269 | 0.98 | NR2E1 (0.97) | NR2E1CYP1A2MEN1KMT2ACYP2C19 | |
| SCHEMBL1394219 | 0.90 | CYP1A2 (0.83) | NR2E1CYP1A2MEN1KMT2ACYP2C19 | |
| SCHEMBL29437208 | 0.90 | CYP1A2 (0.83) | NR2E1CYP1A2MEN1KMT2ACYP2C19 | |
| SCHEMBL29437209 | 0.85 | CYP1A2 (1.00) | NR2E1CYP1A2MEN1KMT2ACYP2C19 | |
| SCHEMBL6483890 | 0.85 | CYP1A2 (1.00) | NR2E1CYP1A2MEN1KMT2ACYP2C19 | |
| SCHEMBL6483883 | 0.85 | CYP1A2 (1.00) | NR2E1CYP1A2MEN1KMT2ACYP2C19 | |
| SCHEMBL8566653 | 0.85 | CYP1A2 (1.00) | NR2E1CYP1A2MEN1KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369209-A1 | R-Diastereomer of N6-[(2-hydroxypropyl)aryl]adenosines | G.D. Searle & Co. (US) | 1990-05-23 | — | — | EP | claimed |
| JP-2164896-A | — | — | None | — | — | JP | disclosed |
| EP-2514739-B1 | Substituted beta-phenyl-alpha-hydroxy propanoic acid, synthesis method and use thereof | UNIV NORTHWEST (CN) | 2016-12-21 | — | — | EP | disclosed |
| EP-2514739-B1 | Substituted beta-phenyl-alpha-hydroxy propanoic acid, synthesis method and use thereof | UNIV NORTHWEST (CN) | 2016-12-21 | — | — | EP | disclosed |
| US-9290503-B2 | Tricyclic compound derivatives useful in the treatment of neoplastic diseases, inflammatory disorders and immunomodulatory disorders | CHEMBRIDGE CORPORATION (US) | 2016-03-22 | — | — | US | disclosed |
| US-9290503-B2 | Tricyclic compound derivatives useful in the treatment of neoplastic diseases, inflammatory disorders and immunomodulatory disorders | CHEMBRIDGE CORPORATION (US) | 2016-03-22 | — | — | US | disclosed |
| US-9034798-B2 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | CAPROTEC BIOANALYTICS GMBH (DE) | 2015-05-19 | — | — | US | disclosed |
| US-20140228350-A1 | TRICYCLIC COMPOUND DERIVATIVES USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES, INFLAMMATORY DISORDERS AND IMMUNOMODULATORY DISORDERS | CHEMBRIDGE CORPORATION (US) | 2014-08-14 | — | — | US | disclosed |
| US-20140228350-A1 | TRICYCLIC COMPOUND DERIVATIVES USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES, INFLAMMATORY DISORDERS AND IMMUNOMODULATORY DISORDERS | CHEMBRIDGE CORPORATION (US) | 2014-08-14 | — | — | US | disclosed |
| US-8569481-B2 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | PHARMACEUTICALS, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| JP-H02164896-A | R-DIASTEREOMER OF ADENOSINE DERIVATIVE | G D SEARLE & CO | 1990-06-25 | — | — | JP | disclosed |
| EP-0369209-A1 | R-Diastereomer of N6-[(2-hydroxypropyl)aryl]adenosines | G.D. Searle & Co. (US) | 1990-05-23 | — | — | EP | disclosed |
| EP-0199845-A1 | Imidazolylalkylguanidin derivatives, process for their preparation and pharmaceutical compositions containing them | HEUMANN PHARMA GMBH & CO (DE) | 1986-11-05 | — | — | EP | disclosed |
| US-4472301-A | REAGENT FOR IMMUNOASSAY | MILES LABORATORIES, INC. (US) | 1984-09-18 | — | — | US | disclosed |
| EP-0095639-A3 | PROPRANOLOL IMMUNOGENS, ANTIBODIES THERETO, TEST DEVICE AND COMPOUNDS FOR PROPRANOLOL IMMUNO ASSAY | MILES LABORATORIES, INC. (US) | 1984-08-08 | — | — | EP | disclosed |
| EP-0095639-A2 | Propranolol immunogens, antibodies thereto, test device and compounds for propranolol immuno assay | MILES LABORATORIES, INC. (US) | 1983-12-07 | — | — | EP | disclosed |
| EP-0095639-A2 | Propranolol immunogens, antibodies thereto, test device and compounds for propranolol immuno assay | MILES LABORATORIES, INC. (US) | 1983-12-07 | — | — | EP | disclosed |
| US-4388308-A | N6 -[(2-Hydroxypropyl)aryl]adenosines | G.D. SEARLE & CO. (US) | 1983-06-14 | — | — | US | disclosed |
| US-4360464-A | Process for production of 1-aryloxy-aminopropane derivatives | TEIKOKU HORMONE MFG. CO. LTD. (JP) | 1982-11-23 | — | — | US | disclosed |
| US-4018824-A | ANTIULCER AND ADRENERGIC BLOCKING AGENTS | TEIKOKU HORMONE MFG. CO., LTD. (JA) | 1977-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140228350-A1 | TRICYCLIC COMPOUND DERIVATIVES USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES, INFLAMMATORY DISORDERS AND IMMUNOMODULATORY DISORDERS | MALT1, TPMT, TSLP | NR2E1 1975/4885CYP1A2 1089/4885MEN1 1427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.