Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL151866 | 1.00 | HTR2A (0.35) | HTR2AHTR6CYP2D6 | |
| Hydrochloric Acid SCHEMBL7190324 | 0.98 | HTR2A (0.34) | HTR2AHTR6CYP2D6 | |
| SCHEMBL5839790 | 0.96 | HTR2A (0.35) | HTR2AHTR6CYP2D6 | |
| Fluoride Ion SCHEMBL1130929 | 0.96 | HTR2A (0.35) | HTR2AHTR6CYP2D6 | |
| Bromide SCHEMBL616105 | 0.96 | HTR2A (0.39) | HTR2AHTR6CYP2D6 | |
| Hydrochloric Acid SCHEMBL8017987 | 0.94 | HTR6 (0.33) | HTR2AHTR6CYP2D6 | |
| Hydrochloric Acid SCHEMBL7518120 | 0.93 | HTR6 (0.32) | HTR2AHTR6 | |
| SCHEMBL6357318 | 0.92 | HTR2A (0.33) | HTR2AHTR6CYP2D6 | |
| Hydrochloric Acid SCHEMBL647120 | 0.92 | HTR6 (0.33) | HTR2AHTR6 | |
| Hydrochloric Acid SCHEMBL648598 | 0.92 | HTR6 (0.33) | HTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080281063-A9 | Ethylene polymers and copolymers with high optical opacity and methods of making the same | SUKHADIA ASHISH M | 2008-11-13 | — | — | US | claimed |
| US-7323524-B2 | Tandem tetramerisation-polymerisation of olefins | SASOL TECHNOLOGY (PTY) LIMITED (ZA) | 2008-01-29 | — | — | US | claimed |
| US-20060128910-A1 | Tandem tetramerisation-polymerisation of olefins | SASOL TECHNOLOGY (PTY) LIMITED (ZA) | 2006-06-15 | — | — | US | claimed |
| EP-1581343-A1 | TANDEM TETRAMERISATION-POLYMERISATION OF OLEFINS | Sasol Technology (PTY) Limited (ZA) | 2005-10-05 | — | — | EP | claimed |
| US-20050203261-A1 | Ethylene polymers and copolymers with high optical opacity and methods of making the same | CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. | 2005-09-15 | — | — | US | claimed |
| WO-2004056480-A1 | TANDEM TETRAMERISATION-POLYMERISATION OF OLEFINS | SASOL TECHNOLOGY (PTY) LIMITED (ZA) | 2004-07-08 | — | — | WO | claimed |
| US-5324801-A | Without ring opening; aluminoxane and a steriorigid metallocene catalyst | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-28 | — | — | US | claimed |
| US-10421921-B2 | Lubricants from mixed alpha-olefin feeds | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2019-09-24 | — | — | US | disclosed |
| EP-1920031-B1 | LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2018-01-10 | — | — | EP | disclosed |
| EP-1529067-B1 | PROCESS FOR THE OLIGOMERIZATION OF A OLEFINS HAVING LOW UNSATURATION | CHEMTURA CORP (US) | 2017-07-05 | — | — | EP | disclosed |
| US-20170137737-A1 | Lubricants from Mixed Alpha-Olefin Feeds | EXXONMOBIL CHEMICAL PATENTS INC. | 2017-05-18 | — | — | US | disclosed |
| US-9593288-B2 | Lubricants from mixed alpha-olefin feeds | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2017-03-14 | — | — | US | disclosed |
| US-20150252279-A1 | Lubricants From Mixed Alpha-Olefin Feeds | EXXONMOBIL CHEMICAL PATENTS INC. | 2015-09-10 | — | — | US | disclosed |
| US-6706828-B2 | BY CATALYSIS WITH METALLOCENE CONTAINING GROUP 4B, 5B, OR6B METAL AND COCATALYST | CROMPTON CORPORATION | 2004-03-16 | — | — | US | disclosed |
| US-20030232937-A1 | Process for the oligomerization of alpha-olefins having low unsaturation | CROMPTON CORPORATION | 2003-12-18 | — | — | US | disclosed |
| EP-0722950-B1 | Process for the preparation of bridged metallocenes | BASELL TECHNOLOGY CO BV (NL) | 2001-09-12 | — | — | EP | disclosed |
| US-6169052-B1 | CATALYST SYSTEM COMPRISING ALUMINOXANE AND A STEREORIGID METALLOCENE COMPOUND | TARGOR GMBH (DE) | 2001-01-02 | — | — | US | disclosed |
| US-5968863-A | REACTION OF LIGAND WITH DOUBLE ANION FOR POLYMERIZATION OF OLEFINS | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 1999-10-19 | — | — | US | disclosed |
| EP-0722950-A1 | Process for the preparation of bridged metallocenes | Montell Technology Company bv (NL) | 1996-07-24 | — | — | EP | disclosed |
| US-5324801-A | Without ring opening; aluminoxane and a steriorigid metallocene catalyst | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-28 | — | — | US | disclosed |