SCHEMBL6484501

SCHEMBL6484501

Cc1c(C)c(C)c2c([nH]c3ccccc32)c1C

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.60
MEN1 O00255 5/20 0.60
KMT2A Q03164 5/20 0.60
PARP1 P09874 2/20 0.60
KDM4E B2RXH2 3/20 0.58
ALDH1A1 P00352 3/20 0.58
HSD17B10 Q99714 3/20 0.58
MAPK1 P28482 3/20 0.58
NPSR1 Q6W5P4 3/20 0.58
LMNA P02545 2/20 0.58
CYP1A2 P05177 2/20 0.58
CYP3A4 P08684 2/20 0.58
CYP2D6 P10635 2/20 0.58
HPGD P15428 2/20 0.58
TSHR P16473 2/20 0.58
NFKB1 P19838 2/20 0.58
APEX1 P27695 2/20 0.58
BLM P54132 2/20 0.58
NPC1 O15118 1/20 0.58
GMNN O75496 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18906311 0.94 PARP1 (0.58) MAPTMEN1KMT2APARP1KDM4E
SCHEMBL554573 0.91 MAPT (0.64) MAPTMEN1KMT2APARP1KDM4E
SCHEMBL15195212 0.88 MEN1 (0.73) MAPTMEN1KMT2APARP1KDM4E
SCHEMBL16432861 0.81 PARP1 (0.54) MAPTMEN1KMT2APARP1KDM4E
SCHEMBL23861154 0.81 MEN1 (0.53) MAPTMEN1KMT2APARP1KDM4E
SCHEMBL4733891 0.81 MEN1 (0.55) MAPTMEN1KMT2APARP1KDM4E
SCHEMBL28932368 0.80 MEN1 (0.56) MAPTMEN1KMT2APARP1KDM4E
SCHEMBL22499402 0.78 PARP1 (0.51) MAPTMEN1KMT2APARP1KDM4E
SCHEMBL29377458 0.78 PARP1 (0.51) MAPTMEN1KMT2APARP1KDM4E
SCHEMBL9623275 0.77 PARP1 (0.57) MAPTMEN1KMT2APARP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108148055-A A kind of D- π-A types organic fluorescence materials and preparation method based on naphthalene 陕西师范大学 2018-06-12 CN claimed
CN-104165936-B The detection method of nitrogen-containing compound in a kind of rock extracts CHINA UNIVERSITY OF GEOSCIENCES (WUHAN) (CN) 2016-03-16 CN claimed
CN-104165936-A Detection method of nitrogen-containing compound from rock extract UNIV CHINA GEOSCIENCES WUHAN 2014-11-26 CN claimed
EP-0210909-B1 ALKYLAMINO AMIDES AND THEIR SALTS, THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1990-03-21 EP claimed
CN-122080034-A Polycyclic aromatic compound and organic electroluminescent element 2026-05-26 CN disclosed
CN-122059973-A Polycyclic aromatic compound, material for organic device, organic electroluminescent element, display device, and lighting device 爱思开新材料捷恩智株式会社 2026-05-19 CN disclosed
EP-4663642-A1 POLYCYCLIC AROMATIC COMPOUND Kyoto University (JP) 2025-12-17 EP disclosed
EP-4635960-A1 POLYCYCLIC AROMATIC COMPOUND Kyoto University (JP) 2025-10-22 EP disclosed
CN-120157693-A Polycyclic aromatic compound and organic electroluminescent element 爱思开新材料捷恩智株式会社 2025-06-17 CN disclosed
CN-120118107-A Polycyclic aromatic compound and organic electroluminescent element 爱思开新材料捷恩智株式会社 2025-06-10 CN disclosed
CN-120040479-A Polycyclic aromatic compound and organic electroluminescent element 爱思开新材料捷恩智株式会社 2025-05-27 CN disclosed
CN-119930662-A Polycyclic aromatic compound, organic electroluminescent element, display device, and lighting device 爱思开新材料捷恩智株式会社 2025-05-06 CN disclosed
EP-1173440-B1 TETRACYCLIC AZEPINOINDOLE COMPOUNDS AS 5-HT RECEPTOR LIGANDS UPJOHN CO (US) 2004-09-15 EP disclosed
US-20040138202-A1 Tetracyclic azepinoindole compounds PHARMACIA AND UPJOHN COMPANY 2004-07-15 US disclosed
US-20020198190-A1 Tetracyclic azepinoindole compounds PHARMACIA & UPJOHN COMPANY 2002-12-26 US disclosed
US-6407092-B1 5-HYDROXYTRYPTAMINE MODULATORS AND ANTISEROTONINE AGENTS; TREATING EATING, SEXUAL, SLEEP, NERVOUS SYSTEM, PSYCHOLOGICAL, AND GASTROINTESTINAL DISORDERS; ANTIDEPRESSANTS, ANXIOLYTIC AGENTS PHARMACIA & UPJOHN COMPANY 2002-06-18 US disclosed
CN-1348454-A Tetracyclic azepinoindole compounds as 5-HT receptor ligands UPJOHN CO (US) 2002-05-08 CN disclosed
EP-1173440-A1 TETRACYCLIC AZEPINOINDOLE COMPOUNDS AS 5-HT RECEPTOR LIGANDS PHARMACIA & UPJOHN COMPANY (US) 2002-01-23 EP disclosed
WO-2000064899-A1 TETRACYCLIC AZEPINOINDOLE COMPOUNDS AS 5-HT RECEPTOR LIGANDS PHARMACIA & UPJOHN COMPANY (US) 2000-11-02 WO disclosed
EP-0210909-B1 ALKYLAMINO AMIDES AND THEIR SALTS, THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1990-03-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040138202-A1 Tetracyclic azepinoindole compounds TPH1, AZI2, CYP1A2 MAPT 2518/4885MEN1 164/4885KMT2A 2669/4885
US-20020198190-A1 Tetracyclic azepinoindole compounds TPH1, AZI2, CYP1A2 MAPT 2518/4885MEN1 164/4885KMT2A 2669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.