Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7073073 | 0.90 | RAD52 (0.42) | METAP2METAP1NPY5RENPP1ITGB3 | |
| SCHEMBL4957389 | 0.86 | METAP2 (0.44) | METAP2METAP1NPY5RENPP1ITGB3 | |
| SCHEMBL9569994 | 0.83 | METAP2 (0.42) | METAP2METAP1NPY5RENPP1ITGB3 | |
| SCHEMBL29208955 | 0.83 | METAP2 (0.42) | METAP2METAP1NPY5RENPP1ITGB3 | |
| SCHEMBL30884953 | 0.83 | METAP2 (0.42) | METAP2METAP1NPY5RENPP1ITGB3 | |
| SCHEMBL4955472 | 0.83 | METAP2 (0.42) | METAP2METAP1NPY5RENPP1ITGB3 | |
| SCHEMBL7851163 | 0.80 | PI4KA (0.49) | METAP2METAP1NPY5RPI4KAPI4K2B | |
| SCHEMBL10852261 | 0.79 | METAP2 (0.39) | METAP2METAP1NPY5RENPP1ITGB3 | |
| SCHEMBL5062499 | 0.79 | METAP2 (0.39) | METAP2METAP1NPY5RPI4KAPI4K2B | |
| SCHEMBL3691689 | 0.79 | PI4KA (0.55) | METAP2METAP1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 16961 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3856736-B1 | NOVEL COMPOUNDS AS NADPH OXIDASE INHIBITORS | CALLIDITAS THERAPEUTICS SUISSE SA (CH) | 2026-05-06 | — | — | EP | claimed |
| US-20260109699-A1 | AZOLE DERIVATIVES AS SHP2 INHIBITORS | IRBM S.P.A. (IT) | 2026-04-23 | — | — | US | claimed |
| US-20260069700-A1 | BRUSH PRODRUGS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2026-03-12 | — | — | US | claimed |
| EP-4648746-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING ALOPECIA | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (IL) | 2025-11-19 | — | — | EP | claimed |
| US-20250332230-A1 | ULCERATIVE COLITIS TREATMENTS IN SELECTED PATIENTS | THERIVA BIOLOGICS INC (US) | 2025-10-30 | — | — | US | claimed |
| EP-4619104-A1 | BICYCLIC HETEROCYCLES AND THEIR USE AS WRN INHIBITORS | Novartis AG (CH) | 2025-09-24 | — | — | EP | claimed |
| EP-4601746-A1 | TRICYCLIC COMPOUNDS AND THEIR USES | Novartis AG (CH) | 2025-08-20 | — | — | EP | claimed |
| EP-4594324-A1 | AZOLE DERIVATIVES AS SHP2 INHIBITORS | IRBM S.P.A. (IT) | 2025-08-06 | — | — | EP | claimed |
| US-20250242046-A1 | ALLOGENEIC HYPOIMMUNE BIOMIMETIC NANOVESICLE FOR THE TREATMENT OF CANCER | MALCOLM THOMAS (US) | 2025-07-31 | — | — | US | claimed |
| US-20250177418-A1 | NEUROACTIVE STEROIDS FOR TREATMENT OF GASTROINTESTINAL DISEASES OR CONDITIONS | SAGE THERAPEUTICS, INC. | 2025-06-05 | — | — | US | claimed |
| US-20010041713-A1 | Treatment or prevention of prostate cancer with a COX-2 selective inhibiting drug | WALDSTREICHER JOANNE (US) | 2001-11-15 | — | — | US | claimed |
| US-20010039952-A1 | ULTRASOUND ENHANCED CHEMOTHERAPY | WALTER A. HACKER, PH. D | 2001-11-15 | — | — | US | claimed |
| US-6308714-B1 | Ultrasound enhanced chemotherapy | CORAJE, INC. | 2001-10-30 | — | — | US | claimed |
| US-20010018919-A1 | Method, apparatus and system for use in treating patient with a drug having an antineoplastic effect to optimize therapy and prevent an adverse drug response | DIMENSIONAL DOSING SYSTEMS, INCORPORATED | 2001-09-06 | — | — | US | claimed |
| WO-2001060365-A1 | TREATMENT OR PREVENTION OF PROSTATE CANCER WITH A COX-2 SELECTIVE INHIBITING DRUG | MERCK & CO., INC. (US) | 2001-08-23 | — | — | WO | claimed |
| WO-2001054688-A1 | TREATMENT OR PREVENTION OF PROSTATE CANCER WITH A COX-2 SELECTIVE INHIBITING DRUG | MERCK & CO., INC. (US) | 2001-08-02 | — | — | WO | claimed |
| CN-1063630-C | Surface modified anticancer nanoparticles | NANNO SYSTEM CO (US) | 2001-03-28 | — | — | CN | claimed |
| CN-1250375-A | Pharmaceutical composition containing shark cartilage extract and antitumor agent for treating tumor | AETERNA LAB INC (CA) | 2000-04-12 | — | — | CN | claimed |
| CN-1244123-A | Kit for inhibiting the growth of cancers, comprising a chemotherapeutic agent and a benzimdazole, and optionally a protentiator | PROCTER & GAMBLE (US) | 2000-02-09 | — | — | CN | claimed |
| CN-1225020-A | Terminal sterilization of biologicals | QUADRANT HOLDING CAMBRIDGE LIM (GB) | 1999-08-04 | — | — | CN | claimed |