SCHEMBL6485160

SCHEMBL6485160

FC(F)(F)Oc1cccs1

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KCNA5 P22460 2/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
ATM Q13315 1/20 0.33
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP9 P14780 1/20 0.33
MMP12 P39900 1/20 0.33
FBP1 P09467 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
MPL P40238 1/20 0.30
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30
TSHR P16473 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3026899 0.76 SMN1; SMN2 (0.38) MMP1MMP2MMP9MMP12FBP1
SCHEMBL24497185 0.76 DAO (0.39) KCNA5MEN1KMT2AMMP1MMP2
SCHEMBL8965381 0.72
SCHEMBL7080993 0.71 MAPT (0.35) MEN1KMT2ASMN1; SMN2MAPTTSHR
SCHEMBL4082360 0.71 FBP1 (0.39) MEN1KMT2AATMMMP1MMP2
SCHEMBL251357 0.71 MGMT (0.40) MEN1KMT2AATMMMP1MMP2
SCHEMBL30039658 0.70 FBP1 (0.40) MEN1KMT2AATMMMP1MMP2
SCHEMBL2040269 0.70 SMN1; SMN2 (0.33) MMP1MMP2MMP9MMP12SMN1; SMN2
SCHEMBL9682640 0.69 MGMT (0.39) MEN1KMT2AATMMMP1MMP2
SCHEMBL15576291 0.69 KMT2A (0.33) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113140793-B High-voltage lithium ion electrolyte and application thereof 山东海容电源材料有限公司 2022-07-12 CN disclosed
US-20050203108-A1 Glucagon antagonists/inverse agonists PFIZER INC 2005-09-15 US disclosed
EP-0934940-A1 CYTOKINE PRODUCTION INHIBITORS, TRIAZEPINE COMPOUNDS, AND INTERMEDIATES THEREOF Japan Tobacco Inc. (JP) 1999-08-11 EP disclosed
US-5807850-A Therapeutic agent for osteoporosis and triazepine compound JAPAN TOBACCO, INC. (JP) 1998-09-15 US disclosed
EP-0792880-A1 OSTEOPOROSIS REMEDY AND TRIAZEPINE COMPOUND Japan Tobacco Inc. (JP) 1997-09-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050203108-A1 Glucagon antagonists/inverse agonists GLP1R, GPR119, GCGR KCNA5 3239/4885MEN1 2079/4885KMT2A 3304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.