Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 12/20 | 0.61 |
| ▸ | GRIA2 | P42262 | 7/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6485210 | 0.99 | GRIK1 (0.60) | GRIK1GRIA2TDP1CNR2KDM4E | |
| SCHEMBL6488414 | 0.76 | GRIK1 (1.00) | GRIK1GRIA2 | |
| Hydrochloric Acid SCHEMBL6486373 | 0.76 | GRIK1 (0.98) | GRIK1GRIA2 | |
| SCHEMBL13390363 | 0.74 | GRIK1 (0.69) | GRIK1GRIA2 | |
| SCHEMBL16060183 | 0.74 | TDP1 (0.60) | TDP1CNR2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL6494432 | 0.74 | GRIK1 (0.44) | GRIK1GRIA2TDP1CNR2KDM4E | |
| SCHEMBL13390373 | 0.73 | GRIK1 (0.66) | GRIK1GRIA2 | |
| SCHEMBL6494209 | 0.73 | GRIK1 (0.74) | GRIK1GRIA2ALDH1A1 | |
| SCHEMBL13390447 | 0.69 | GRIK1 (0.64) | GRIK1GRIA2 | |
| SCHEMBL7061178 | 0.69 | GRIK1 (0.59) | GRIK1GRIA2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6924294-B2 | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 2005-08-02 | — | — | US | disclosed |
| US-20040053961-A1 | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY | 2004-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053961-A1 | Excitatory amino acid receptor antagonists | SLC1A2, SLC1A1, SLC1A3 | GRIK1 12/4885GRIA2 24/4885TDP1 1199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.