Fluoride

Fluoride

SCHEMBL648538

F.O=C(O)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.74
ACLY P53396 2/20 0.44
ALDH1A1 P00352 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TET2 Q6N021 1/20 0.30
TP53 P04637 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31083846 0.97 THRB (0.78) THRBACLYALDH1A1L3MBTL1TET2
SCHEMBL37922 0.97 THRB (0.78) THRBACLYALDH1A1L3MBTL1TET2
SCHEMBL4582407 0.94 THRB (0.74) THRBACLYALDH1A1L3MBTL1TET2
SCHEMBL10694667 0.94 THRB (0.74) THRBACLYALDH1A1L3MBTL1TET2
Phosphine SCHEMBL28772938 0.94 THRB (0.74) THRBACLYALDH1A1L3MBTL1TET2
Ammonia Solution, Strong SCHEMBL1395115 0.94 THRB (0.74) THRBACLYALDH1A1L3MBTL1TET2
SCHEMBL3086542 0.94 THRB (0.74) THRBACLYALDH1A1L3MBTL1TET2
Hydrochloric Acid SCHEMBL808878 0.94 THRB (0.74) THRBACLYALDH1A1L3MBTL1TET2
Ammonia Solution, Strong SCHEMBL11050684 0.94 THRB (0.74) THRBACLYALDH1A1L3MBTL1TET2
SCHEMBL28573086 0.94 THRB (0.74) THRBACLYALDH1A1L3MBTL1TET2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2021379-B1 FLUORINATED SURFACTANTS 3M INNOVATIVE PROPERTIES CO (US) 2014-11-26 EP disclosed
US-8119750-B2 Explosion taming surfactants for the production of perfluoropolymers 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-02-21 US disclosed
EP-2021379-A1 FLUORINATED SURFACTANTS 3M Innovative Properties Company (US) 2009-02-11 EP disclosed
US-20080015319-A1 EXPLOSION TAMING SURFACTANTS FOR THE PRODUCTION OF PERFLUOROPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY 2008-01-17 US disclosed
WO-2007140112-A1 FLUORINATED SURFACTANTS 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-12-06 WO disclosed
US-20070276103-A1 Fluorinated Surfactants 3M INNOVATIVE PROPERTIES COMPANY 2007-11-29 US disclosed
US-4603017-A HEAT EXCHANGING FLUIDS, LUBRICANTS HOECHST ATKIENGESELLSCHAFT (DE) 1986-07-29 US disclosed
US-4524031-A HEAT TRANSFER FLUIDS HOECHST AKTIENGESELLSCHAFT (DE) 1985-06-18 US disclosed
US-4420433-A REACTION WITH SILICON TETRACHLORIDE OR TITANIUM TETRACHLORIDE BAYER AKTIENGESELLSCHAFT (DE) 1983-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070276103-A1 Fluorinated Surfactants FLNA, FLNB, PHOSPHO1 THRB 4565/4885ACLY 3764/4885ALDH1A1 3440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.