SCHEMBL6486

SCHEMBL6486

CCOP(=O)(C#N)OCC

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.54
TSHR P16473 2/20 0.50
TP53 P04637 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
PPARD Q03181 2/20 0.37
LMNA P02545 2/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL27734360 0.97 TSHR (0.52) ACHETSHRTP53TDP1PPARD
Methyl Alcohol SCHEMBL31536354 0.95 ACHE (0.50) ACHETSHRTP53TDP1PPARD
Carbimide SCHEMBL22721299 0.91 ACHE (0.47) ACHETSHRTP53TDP1PPARD
SCHEMBL7443555 0.89 ACHE (0.50) ACHETSHRTP53TDP1PPARD
SCHEMBL8328394 0.82 ACHE (0.44) ACHETSHRTP53TDP1PPARD
SCHEMBL8385521 0.82 ACHE (0.53) ACHETSHRTP53TDP1PPARD
SCHEMBL8332957 0.82 ACHE (0.44) ACHETSHRTP53TDP1PPARD
SCHEMBL5033275 0.77 TSHR (0.55) ACHETSHRTP53TDP1PPARD
SCHEMBL1618533 0.74
SCHEMBL15649351 0.74 ACHE (0.40) ACHETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8622 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747621-A1 SPECIFIC AND LABEL-FREE SENSING OF SMALL MOLECULE TARGETS USING BIOLOGICAL TRANSISTORS B.G. Negev Technologies and Applications Ltd., at Ben-Gurion University (IL) 2026-05-27 EP claimed
CN-117304919-B Organic fluorescent sensing array for selectively distinguishing and detecting sarin and preparation method thereof INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2026-05-26 CN claimed
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 US claimed
US-12508321-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers HANGZHOU DAC BIOTECH CO., LTD. (CN) 2025-12-30 US claimed
US-12496351-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers HANGZHOU DAC BIOTECH CO., LTD. (CN) 2025-12-16 US claimed
US-12466855-B2 Labeled oxytocin and method of manufacture and use TONIX PHARMA LIMITED (IE) 2025-11-11 US claimed
EP-4628492-A1 PREPARATION METHOD FOR LINKER-DRUG CONJUGATE AND INTERMEDIATE THEREOF Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. (CN) 2025-10-08 EP claimed
EP-3927685-B1 A PROCESS FOR THE SYNTHESIS ANTHRANILIC DIAMIDE COMPOUNDS AND INTERMEDIATES THEREOF PI INDUSTRIES LTD (IN) 2025-10-08 EP claimed
EP-4585268-A2 SOLID FORMS OF ISOQUINOLINONE DERIVATIVES, PROCESS OF MAKING, COMPOSITIONS COMPRISING, AND METHODS OF USING THE SAME Twelve Therapeutics, Inc. (US) 2025-07-16 EP claimed
CN-116120239-B Aromatic six-membered cycloimidazole derivative, and preparation method and application thereof 沈阳药科大学 2025-06-24 CN claimed
WO-1995004049-A1 PIPERAZINE DERIVATIVES AS α1A-ADRENERGIC RECEPTOR ANTAGONISTS RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) 1995-02-09 WO claimed
EP-0612762-A1 Elucidation and synthesis of selected pentapeptides ARIZONA BOARD OF REGENTS (US) 1994-08-31 EP claimed
EP-0611775-A2 Human cancer inhibitory pentapeptide amides ARIZONA BOARD OF REGENTS (US) 1994-08-24 EP claimed
US-5189023-A Hypotensive agent AMERICAN CYANAMID COMPANY (US) 1993-02-23 US claimed
US-5076973-A Cell growth inhibitor;leukemia ARIZONA BOARD OF REGENTS (US) 1991-12-31 US claimed
EP-0427939-A2 Renin inhibitors AMERICAN CYANAMID COMPANY (US) 1991-05-22 EP claimed
US-4978744-A Synthesis of dolastatin 10 ARIZONA BOARD OF REGENTS (US) 1990-12-18 US claimed
EP-0376040-A2 N-phosphinyl di-and tripeptides as renin inhibitors AMERICAN CYANAMID COMPANY (US) 1990-07-04 EP claimed
EP-0376012-A2 Renin inhibitors AMERICAN CYANAMID COMPANY (US) 1990-07-04 EP claimed
US-4401592-A REACTION PRODUCT OF AN ANTIBODY WITH AN ANTIBIOTIC, ANTIMETABOLIC SUBSTANCE OR ALKYLATING AGENT KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1983-08-30 US claimed