SCHEMBL8328394

SCHEMBL8328394

CCOP(=O)(C#N)OS(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.44
TSHR P16473 2/20 0.39
TP53 P04637 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
LMNA P02545 1/20 0.31
KMT2A Q03164 1/20 0.31
PPARD Q03181 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6486 0.82 ACHE (0.54) ACHETSHRTP53TDP1LMNA
SCHEMBL8329217 0.82
Phosphine SCHEMBL27734360 0.80 TSHR (0.52) ACHETSHRTP53TDP1LMNA
Methyl Alcohol SCHEMBL31536354 0.78 ACHE (0.50) ACHETSHRTP53TDP1LMNA
Carbimide SCHEMBL22721299 0.74 ACHE (0.47) ACHETSHRTP53TDP1LMNA
SCHEMBL7443555 0.72 ACHE (0.50) ACHETSHRTP53TDP1LMNA
SCHEMBL8332957 0.71 ACHE (0.44) ACHETSHRTP53TDP1LMNA
SCHEMBL8385521 0.71 ACHE (0.53) ACHETSHRTP53TDP1LMNA
SCHEMBL5033275 0.66 TSHR (0.55) ACHETSHRTP53TDP1PPARD
SCHEMBL12653888 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0948506-A1 CYANOPHOSPHONATE DERIVATIVES MONSANTO COMPANY (US) 1999-10-13 EP claimed
US-5935542-A Cyanphosphonate derivatives and method for their preparation MONSANTO COMPANY (US) 1999-08-10 US claimed
WO-1998029422-A1 CYANOPHOSPHONATE DERIVATIVES MONSANTO COMPANY (US) 1998-07-09 WO claimed
EP-0948506-A1 CYANOPHOSPHONATE DERIVATIVES MONSANTO COMPANY (US) 1999-10-13 EP disclosed
US-5935542-A Cyanphosphonate derivatives and method for their preparation MONSANTO COMPANY (US) 1999-08-10 US disclosed
WO-1998029422-A1 CYANOPHOSPHONATE DERIVATIVES MONSANTO COMPANY (US) 1998-07-09 WO disclosed