Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | KCNN2 | Q9H2S1 | 2/20 | 0.48 |
| ▸ | KCNN3 | Q9UGI6 | 2/20 | 0.48 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9585990 | 0.82 | LMNA (0.79) | LMNAKDM4EALDH1A1HSD17B10MAPK1 | |
| SCHEMBL30585089 | 0.82 | LMNA (0.79) | LMNAKDM4EALDH1A1HSD17B10MAPK1 | |
| SCHEMBL8236635 | 0.80 | LMNA (0.79) | LMNAKDM4EALDH1A1HSD17B10MAPK1 | |
| SCHEMBL11706207 | 0.77 | PDE4D (0.53) | LMNAKDM4EALDH1A1HSD17B10MAPK1 | |
| SCHEMBL12633789 | 0.76 | LMNA (0.68) | LMNAKDM4EALDH1A1HSD17B10MAPK1 | |
| Laudanosine SCHEMBL466528 | 0.74 | LMNA (1.00) | LMNAKDM4EALDH1A1HSD17B10MAPK1 | |
| Laudanosine SCHEMBL29822950 | 0.74 | LMNA (1.00) | LMNAKDM4EALDH1A1HSD17B10MAPK1 | |
| Laudanosine SCHEMBL466529 | 0.74 | LMNA (1.00) | LMNAKDM4EALDH1A1HSD17B10MAPK1 | |
| Laudanosine SCHEMBL30816021 | 0.74 | LMNA (1.00) | LMNAKDM4EALDH1A1HSD17B10MAPK1 | |
| Laudanosine SCHEMBL6130845 | 0.74 | LMNA (1.00) | LMNAKDM4EALDH1A1HSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6958398-B1 | Methods for making thebaine or its acid salts | EURO-CELTIQUE S.A. (LU) | 2005-10-25 | — | — | US | disclosed |
| US-6372756-B1 | NARCOTICS OR ANALGESICS | AVMAX, INC. | 2002-04-16 | — | — | US | disclosed |
| EP-1056455-A4 | EPIMORPHIAN COMPOUND AND ITS USE | AVMAX INC (US) | 2000-12-06 | — | — | EP | disclosed |
| EP-1056455-A1 | EPIMORPHIAN COMPOUND AND ITS USE | Avmax, Inc. (US) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999042105-A1 | EPIMORPHIAN COMPOUND AND ITS USE | AVMAX, INC. (US) | 1999-08-26 | — | — | WO | disclosed |