Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1647530 | 0.88 | HTR6 (0.36) | HTR6 | |
| SCHEMBL6274716 | 0.82 | HTR6 (0.37) | HTR6 | |
| SCHEMBL946511 | 0.82 | HTR6 (0.39) | HTR6 | |
| SCHEMBL8717579 | 0.81 | HTR6 (0.36) | HTR6 | |
| SCHEMBL4453791 | 0.80 | HTR6 (0.38) | HTR6 | |
| SCHEMBL11199604 | 0.76 | HTR6 (0.34) | HTR6 | |
| SCHEMBL2778573 | 0.75 | — | — | |
| SCHEMBL236881 | 0.73 | CYP2D6 (0.30) | — | |
| SCHEMBL2241191 | 0.73 | — | — | |
| SCHEMBL731008 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897210-B2 | Quinazoline derivatives and pharmaceutical compositions containing them | ZENECA LIMITED (GB) | 2005-05-24 | — | — | US | disclosed |