Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6484306 | 0.94 | KDR (0.44) | HSPD1HSPE1MAPTCYSLTR2CYSLTR1 | |
| SCHEMBL6477587 | 0.93 | HSPD1 (0.43) | HSPD1HSPE1TP53MAPTPPARG | |
| SCHEMBL6487120 | 0.81 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1 | |
| SCHEMBL9721974 | 0.80 | KDR (0.58) | TP53POLBMAPTPPARGPPARA | |
| SCHEMBL9721949 | 0.79 | MAPT (0.58) | TP53POLBMAPTPPARGPPARA | |
| SCHEMBL6476719 | 0.79 | CYSLTR2 (0.49) | HSPD1HSPE1CYSLTR2CYSLTR1 | |
| SCHEMBL6476535 | 0.79 | CYSLTR2 (0.40) | CYSLTR2CYSLTR1 | |
| SCHEMBL6488956 | 0.79 | AGXT (0.42) | CYSLTR2CYSLTR1 | |
| SCHEMBL6484697 | 0.79 | PPARA (0.49) | TP53MAPTPPARACYSLTR2CYSLTR1 | |
| SCHEMBL6485332 | 0.78 | CYSLTR2 (0.41) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6933322-B2 | Substituted naphthylenes for the treatment of non-insulin dependent diabetes mellitus | WYETH (US) | 2005-08-23 | — | — | US | disclosed |