Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22832200 | 0.98 | CYP1A2 (0.52) | CYP1A2TSHRHDAC1HDAC2HDAC6 | |
| Hydrochloric Acid SCHEMBL1093848 | 0.98 | CYP1A2 (0.52) | CYP1A2TSHRHDAC1HDAC2HDAC6 | |
| Acetic Acid SCHEMBL5167214 | 0.94 | CYP1A2 (0.48) | CYP1A2TSHRHDAC1HDAC2HDAC6 | |
| SCHEMBL901575 | 0.93 | CYP1A2 (0.47) | CYP1A2TSHRHDAC1HDAC2HDAC6 | |
| SCHEMBL7697296 | 0.91 | PAOX (0.50) | CYP1A2TSHRHDAC1HDAC2HDAC6 | |
| SCHEMBL22834112 | 0.91 | PAOX (0.50) | CYP1A2TSHRHDAC1HDAC2HDAC6 | |
| SCHEMBL21611683 | 0.91 | PAOX (0.50) | CYP1A2TSHRHDAC1HDAC2HDAC6 | |
| SCHEMBL931564 | 0.91 | PAOX (0.50) | CYP1A2TSHRHDAC1HDAC2HDAC6 | |
| SCHEMBL1952053 | 0.91 | PAOX (0.50) | CYP1A2TSHRHDAC1HDAC2HDAC6 | |
| SCHEMBL3365775 | 0.91 | PAOX (0.50) | CYP1A2TSHRHDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 964 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119988863-A | Preparation process of Chinese patent medicine for treating hypertension based on big data analysis | 北京圣君中医药科技研究院 | 2025-05-13 | — | — | CN | claimed |
| CN-118459451-A | Phenyl urea compound and preparation method and application thereof | 四川大学 | 2024-08-09 | — | — | CN | claimed |
| CN-114317450-B | Hybridoma cell strain secreting Flurobendiamide monoclonal antibody and application thereof | 江南大学 | 2023-10-27 | — | — | CN | claimed |
| EP-3666767-B1 | PHTHALAZINONE DERIVATIVES, METHOD FOR THEIR PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION COMPRISING THEM, AND THEIR USE | SHANGHAI INST MATERIA MEDICA CAS (CN) | 2021-12-01 | — | — | EP | claimed |
| US-11040952-B2 | Phthalazinone compound, method for preparation thereof, pharmaceutical composition thereof, and use thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2021-06-22 | — | — | US | claimed |
| CN-109134429-B | Phthalazinone compound, preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2021-06-01 | — | — | CN | claimed |
| EP-3666767-A1 | PYRIDAZINONE COMPOUND, METHOD FOR PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2020-06-17 | — | — | EP | claimed |
| US-20200181109-A1 | PHTHALAZINONE COMPOUND, METHOD FOR PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2020-06-11 | — | — | US | claimed |
| CN-107365342-B | Aldosterone derivative, immunogene and synthetic method, specific antibody and detection reagent and preparation method, kit | 苏州博源医疗科技有限公司 | 2019-08-06 | — | — | CN | claimed |
| CN-107382243-A | A kind of heat-insulating heat-preserving material and preparation method thereof | 湖州钟泰隔热材料有限公司 | 2017-11-24 | — | — | CN | claimed |
| CN-107365342-A | Aldosterone derivative, immunogene and synthetic method, specific antibody and detection reagent and preparation method, kit | 苏州博源医疗科技有限公司 | 2017-11-21 | — | — | CN | claimed |
| US-20150274628-A1 | MULTIFUNCTIONAL RADICAL QUENCHERS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2015-10-01 | — | — | US | claimed |
| EP-2906207-A1 | MULTIFUNCTIONAL RADICAL QUENCHERS | Arizona Board of Regents on behalf of Arizona State University (US) | 2015-08-19 | — | — | EP | claimed |
| CN-104557908-A | Tetrahydroprotoberberine compounds, and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2015-04-29 | — | — | CN | claimed |
| WO-2014059158-A1 | MULTIFUNCTIONAL RADICAL QUENCHERS | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AN ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2014-04-17 | — | — | WO | claimed |
| EP-1140895-B1 | THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-03-24 | — | — | EP | claimed |
| EP-1064253-B1 | ANTI-TUMOUR AGENTS | ASTRAZENECA AB (SE) | 2003-01-29 | — | — | EP | claimed |
| US-6346633-B1 | TERT-AMINOPHENYLESTER OF ACID | ASTRAZENECA AB (SE) | 2002-02-12 | — | — | US | claimed |
| EP-1064253-A1 | ANTI-TUMOUR AGENTS | AstraZeneca AB (SE) | 2001-01-03 | — | — | EP | claimed |
| WO-1999048857-A1 | ANTI-TUMOUR AGENTS | ASTRAZENECA AB (SE) | 1999-09-30 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200181109-A1 | PHTHALAZINONE COMPOUND, METHOD FOR PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | POLRMT, POLN, HCCS | CYP1A2 1001/4885TSHR 4750/4885HDAC1 523/4885 |
| US-20150274628-A1 | MULTIFUNCTIONAL RADICAL QUENCHERS | SQOR, UQCRC1, PRDX5 | CYP1A2 368/4885TSHR 1366/4885HDAC1 2148/4885 |
| US-11040952-B2 | Phthalazinone compound, method for preparation thereof, pharmaceutical composition thereof, and use thereof | POLRMT, POLN, HCCS | CYP1A2 1001/4885TSHR 4750/4885HDAC1 523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.