SCHEMBL6487501

SCHEMBL6487501

CCCCCCSc1ccc(C(=O)O)cc1

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.62
THRB P10828 1/20 0.62
PLK1 P53350 4/20 0.61
TP53 P04637 1/20 0.58
TSHR P16473 1/20 0.58
PLA2G4B P0C869 4/20 0.57
RARB P10826 7/20 0.54
MEN1 O00255 1/20 0.53
ALDH1A1 P00352 1/20 0.53
RARA P10276 1/20 0.53
MAPT P10636 1/20 0.53
MTOR P42345 1/20 0.53
KMT2A Q03164 1/20 0.53
PLA2G4A P47712 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22438945 1.00 THRA (0.62) THRATHRBPLK1TP53TSHR
SCHEMBL7829330 1.00 THRA (0.62) THRATHRBPLK1TP53TSHR
SCHEMBL28477008 1.00 THRA (0.62) THRATHRBPLK1TP53TSHR
SCHEMBL9365114 1.00 THRA (0.62) THRATHRBPLK1TP53TSHR
SCHEMBL12080799 1.00 THRA (0.62) THRATHRBPLK1TP53TSHR
SCHEMBL11573788 0.98 THRA (0.60) THRATHRBPLK1TP53TSHR
SCHEMBL10528100 0.95 RARB (0.61) THRATHRBPLK1TP53TSHR
SCHEMBL10528096 0.95 RARB (0.61) THRATHRBPLK1TP53TSHR
SCHEMBL10529851 0.95 RARB (0.61) THRATHRBPLK1TP53TSHR
SCHEMBL10536522 0.95 RARB (0.61) THRATHRBPLK1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8815478-B2 Colored curable composition, resist liquid, ink for inkjet printing, color filter, method of producing color filter, solid-state image sensor, liquid crystal display, organic EL display, image display device and colorant compound FUJIFILM CORPORATION (JP) 2014-08-26 US disclosed
US-20120264039-A1 COLORED CURABLE COMPOSITION, RESIST LIQUID, INK FOR INKJET PRINTING, COLOR FILTER, METHOD OF PRODUCING COLOR FILTER, SOLID-STATE IMAGE SENSOR, LIQUID CRYSTAL DISPLAY, ORGANIC EL DISPLAY, IMAGE DISPLAY DEVICE AND COLORANT COMPOUND FUJIFILM CORPORATION (JP) 2012-10-18 US disclosed
US-6887863-B2 Hydrazide and alkoxyamide angiogenesis inhibitors ABBOTT LABORATORIES (US) 2005-05-03 US disclosed
EP-1272456-B1 HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS ABBOTT LAB (US) 2004-10-27 EP disclosed
US-20040167126-A1 Hydrazide and alkoxyamide angiogenesis inhibitors ABBVIE INC. 2004-08-26 US disclosed
EP-1272456-A1 HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS Abbott Laboratories (US) 2003-01-08 EP disclosed
US-20020002152-A1 Hydrazide and alkoxyamide angiogenesis inhibitors ABBOTT LABORATORIES 2002-01-03 US disclosed
WO-2001079157-A1 HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS ABBOTT LABORATORIES (US) 2001-10-25 WO disclosed
US-4014932-A ANTHELMINTICS, PESTICIDES, MITICIDES, INSECTICIDES THE UPJOHN COMPANY (US) 1977-03-29 US disclosed
US-3980685-A Magnesium-aluminum containing complexes of organic anions of central nervous system affecting compounds KYOWA CHEMICAL INDUSTRY CO., LTD. (JA) 1976-09-14 US disclosed
US-3931318-A ANTHELMINTICS, PESTICIDES THE UPJOHN COMPANY (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120264039-A1 COLORED CURABLE COMPOSITION, RESIST LIQUID, INK FOR INKJET PRINTING, COLOR FILTER, METHOD OF PRODUCING COLOR FILTER, SOLID-STATE IMAGE SENSOR, LIQUID CRYSTAL DISPLAY, ORGANIC EL DISPLAY, IMAGE DISPLAY DEVICE AND COLORANT COMPOUND CDYL, RET, NLRP1 THRA 3268/4885THRB 3859/4885PLK1 2393/4885
US-20040167126-A1 Hydrazide and alkoxyamide angiogenesis inhibitors METAP2, METAP1, ANPEP THRA 4083/4885THRB 2778/4885PLK1 3643/4885
US-20020002152-A1 Hydrazide and alkoxyamide angiogenesis inhibitors METAP2, METAP1, ANPEP THRA 4083/4885THRB 2778/4885PLK1 3643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.