Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.53 |
| ▸ | FAAH | O00519 | 3/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.53 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4300433 | 0.79 | MGLL (0.65) | MGLLFAAHHSP90AA1TLR9ALDH1A1 | |
| SCHEMBL38665905 | 0.76 | GNAI3 (0.53) | PTGS2KDM4EHRH2HRH1 | |
| SCHEMBL6484741 | 0.75 | KDM4E (0.41) | ALDH1A1NPSR1PTGS2KDM4EKDM1A | |
| SCHEMBL6485200 | 0.75 | KDM4E (0.41) | ALDH1A1NPSR1PTGS2KDM4EKDM1A | |
| SCHEMBL20376410 | 0.74 | HRH2 (0.52) | PTGS2KDM4EKDM1AHRH2HRH1 | |
| SCHEMBL4508386 | 0.74 | KDM1A (0.42) | ALDH1A1SMN1; SMN2NPSR1PTGS2KDM4E | |
| SCHEMBL258626 | 0.73 | MGLL (1.00) | MGLLFAAHHSP90AA1TLR9ALDH1A1 | |
| SCHEMBL549065 | 0.73 | MGLL (1.00) | MGLLFAAHHSP90AA1TLR9ALDH1A1 | |
| SCHEMBL20351983 | 0.73 | MGLL (1.00) | MGLLFAAHHSP90AA1TLR9ALDH1A1 | |
| SCHEMBL818349 | 0.73 | MGLL (1.00) | MGLLFAAHHSP90AA1TLR9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6861432-B2 | Piperazine derivatives that destabilize androgen receptors | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-03-01 | — | — | US | disclosed |