Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 4/20 | 0.36 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.35 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6492529 | 0.93 | PIK3C2B (0.38) | DCTPP1PIK3C2BTP53MAPTALOX5AP | |
| SCHEMBL6496471 | 0.93 | DCTPP1 (0.37) | DCTPP1PIK3C2BTP53MAPTALOX5AP | |
| SCHEMBL6500738 | 0.93 | PIK3C2B (0.38) | DCTPP1PIK3C2BTP53ALOX5APAGTR1 | |
| SCHEMBL6498346 | 0.91 | CD274 (0.37) | DCTPP1PIK3C2BTP53MAPTALOX5AP | |
| SCHEMBL6498787 | 0.89 | BCL2 (0.40) | DCTPP1PIK3C2BTP53MAPTALOX5AP | |
| SCHEMBL6499859 | 0.88 | DCTPP1 (0.42) | DCTPP1PIK3C2BBCL2MCL1 | |
| SCHEMBL6500643 | 0.87 | ALOX5AP (0.40) | DCTPP1PIK3C2BALOX5APBCL2MCL1 | |
| SCHEMBL6502905 | 0.87 | PIK3C2B (0.41) | DCTPP1PIK3C2BALOX5APBCL2MCL1 | |
| SCHEMBL6488163 | 0.85 | PIK3C2B (0.37) | DCTPP1PIK3C2BTP53MAPTALOX5AP | |
| SCHEMBL6498230 | 0.85 | ALOX5AP (0.38) | DCTPP1TP53MAPTALOX5APAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | BDKRB1 501/4885DCTPP1 1534/4885PIK3C2B 2433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.