Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.61 |
| ▸ | MAOB | P27338 | 5/20 | 0.34 |
| ▸ | CALML3 | P27482 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SDHA | P31040 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6210242 | 0.87 | MAOA (0.71) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL6478555 | 0.87 | MAOA (0.44) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL6212143 | 0.86 | CALML3 (0.46) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL6480046 | 0.85 | MAOA (0.68) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL6478891 | 0.82 | MAOA (0.55) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL6478029 | 0.81 | MAOA (0.39) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL4703583 | 0.81 | MAOA (0.68) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL4705310 | 0.80 | MAOA (0.74) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL6478993 | 0.80 | MAOA (0.45) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL6209788 | 0.80 | MAOA (0.45) | MAOAMAOBCALML3LMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875784-B2 | Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives | PHARMACIA & UPJOHN COMPANY (US) | 2005-04-05 | — | — | US | disclosed |
| US-20040127530-A1 | Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127530-A1 | Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives | OXA1L, CYP1B1, MT-CO1 | MAOA 743/4885MAOB 739/4885CALML3 2904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.