Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6497504 | 0.92 | ALOX5AP (0.45) | ALOX5APMAPTPPARGTP53MEN1 | |
| SCHEMBL6488725 | 0.88 | ALOX5AP (0.37) | ALOX5APMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL6500385 | 0.87 | PPARG (0.45) | ALOX5APMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL6491428 | 0.85 | BCL2 (0.46) | ALOX5APMAPTPPARGTP53 | |
| SCHEMBL6500991 | 0.85 | ALOX5AP (0.42) | ALOX5APMAPTALDH1A1SMN1; SMN2PPARG | |
| SCHEMBL6493004 | 0.82 | PDE2A (0.47) | ALOX5APPPARG | |
| SCHEMBL6496340 | 0.82 | PPARG (0.41) | ALOX5APMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL6301641 | 0.82 | PDE2A (0.51) | MAPTALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL6496471 | 0.82 | DCTPP1 (0.37) | ALOX5APMAPTALDH1A1SMN1; SMN2GAA | |
| SCHEMBL6492244 | 0.81 | PPARG (0.46) | ALOX5APPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | ALOX5AP 4663/4885MAPT 3168/4885ALDH1A1 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.