Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pinoxaden Dione SCHEMBL64757 | 0.77 | TSHR (0.39) | KMT2ALMNAHSD17B10MEN1TSHR | |
| SCHEMBL6488593 | 0.72 | ALDH1A1 (0.36) | LMNAL3MBTL1TSHRCYP2A13HPGD | |
| SCHEMBL6810634 | 0.72 | SMN1; SMN2 (0.41) | LMNAL3MBTL1TSHR | |
| SCHEMBL16592315 | 0.71 | GAA (0.32) | TSHRGAA | |
| SCHEMBL8280540 | 0.68 | CYP3A4 (0.41) | KMT2ALMNAMEN1CYP2A13GAA | |
| SCHEMBL16592340 | 0.66 | TSHR (0.34) | TSHR | |
| SCHEMBL11989371 | 0.63 | PRKDC (0.38) | KMT2ALMNAMEN1 | |
| SCHEMBL4459107 | 0.63 | HPGD (0.31) | KMT2ATSHRHPGD | |
| SCHEMBL22661242 | 0.63 | CNR2 (0.32) | KMT2AMEN1CNR2CNR1 | |
| SCHEMBL12022374 | 0.62 | PRKDC (0.38) | LMNAL3MBTL1GAACNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050090399-A1 | Phenyl substituted heterocyclic compounds useful as herbicides | FRIEDMANN ADRIAN A (GB) | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090399-A1 | Phenyl substituted heterocyclic compounds useful as herbicides | DDT, PAH, CYP1A1 | KMT2A 811/4885LMNA 4034/4885HSD17B10 561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.