Pinoxaden Dione

Pinoxaden Dione

SCHEMBL64757

CCc1cc(C)cc(CC)c1C1C(=O)N2CCOCCN2C1=O

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
GAA P10253 2/20 0.38
TP53 P04637 1/20 0.36
ALDH1A1 P00352 2/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
HSD17B10 Q99714 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
ATM Q13315 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
PDE4D Q08499 1/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
POLB P06746 2/20 0.33
KDM4E B2RXH2 1/20 0.33
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4459107 0.86 HPGD (0.31) TSHRHTTSMN1; SMN2ALDH1A1KMT2A
SCHEMBL6810634 0.83 SMN1; SMN2 (0.41) TSHRHTTSMN1; SMN2TP53ALDH1A1
SCHEMBL14335449 0.79
SCHEMBL16592315 0.78 GAA (0.32) TSHRHTTSMN1; SMN2GAAPOLB
SCHEMBL6488155 0.77 KMT2A (0.34) TSHRGAAHSD17B10MEN1KMT2A
SCHEMBL22504320 0.77 SMN1; SMN2 (0.34) TSHRHTTSMN1; SMN2GAATP53
SCHEMBL12774640 0.77
SCHEMBL6488593 0.77 ALDH1A1 (0.36) TSHRHTTSMN1; SMN2GAAALDH1A1
SCHEMBL22661242 0.74 CNR2 (0.32) MAPTMEN1KMT2AKDM4EHKDC1
SCHEMBL8280540 0.74 CYP3A4 (0.41) HTTGAAALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12516069-B2 Process for the preparation of pyrazole-oxadiazepine GHARDA CHEMICALS LIMITED (IN) 2026-01-06 US claimed
US-20240059707-A1 PROCESS FOR THE PREPARATION OF PYRAZOLE-OXADIAZEPINE GHARDA CHEMICALS LIMITED (IN) 2024-02-22 US claimed
EP-4259611-A1 A PROCESS FOR THE PREPARATION OF PYRAZOLE-OXADIAZEPINE Gharda Chemicals Limited (IN) 2023-10-18 EP claimed
CN-111440192-B Method for preparing pinoxaden intermediate through micro-channel 山东华科化工有限公司 2022-11-25 CN claimed
WO-2022123541-A1 A PROCESS FOR THE PREPARATION OF PYRAZOLE-OXADIAZEPINE GHARDA CHEMICALS LIMITED (IN) 2022-06-16 WO claimed
US-12516069-B2 Process for the preparation of pyrazole-oxadiazepine GHARDA CHEMICALS LIMITED (IN) 2026-01-06 US disclosed
US-12446576-B2 Agrochemical formulation containing a sulfopolymer EASTMAN CHEMICAL COMPANY (US) 2025-10-21 US disclosed
CN-119661554-A Pinoxaden and its preparing process Process for the preparation of esters 蚌埠学院 2025-03-21 CN disclosed
US-20250057153-A1 Maleated Natural Oil Derivatives As Agrochemical Inert Ingredients INDORAMA VENTURES OXIDES LLC 2025-02-20 US disclosed
CN-118184600-A Preparation method and application of [1,4,5] oxydiazepane 上海农帆生物科技有限公司 2024-06-14 CN disclosed
US-20240059707-A1 PROCESS FOR THE PREPARATION OF PYRAZOLE-OXADIAZEPINE GHARDA CHEMICALS LIMITED (IN) 2024-02-22 US disclosed
US-20230329237-A1 MUSA PLANTS, FIELDS CONTAINING SUCH PLANTS TAMINCO BV (BE) 2023-10-19 US disclosed
WO-2004017734-A1 MICROENCAPSULATED AGROCHEMICAL COMPOSITION SYNGENTA LIMITED (GB) 2004-03-04 WO disclosed
EP-1209975-B1 HERBICIDAL COMPOSITION SYNGENTA PARTICIPATIONS AG (CH) 2003-11-12 EP disclosed
EP-1183317-B1 PROCESS FOR THE PREPARATION OF HERBICIDAL DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2003-09-17 EP disclosed
WO-2003062244-A1 PHENYL SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL AS HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2003-07-31 WO disclosed
US-6552187-B1 Cyclization condensation of arylmalonic acid diamides or arylmalonic acid monoamides with hydrazine derivatives forming substituted 3-hydroxy-4-aryl-5-oxopyrazolines; high yield and purity SYNGENTA CROP PROTECTION, INC. 2003-04-22 US disclosed
WO-2003022048-A1 NOVEL COMPOUNDS SYNGENTA LIMITED (GB) 2003-03-20 WO disclosed
EP-1209975-A1 HERBICIDAL COMPOSITION Syngenta Participations AG (CH) 2002-06-05 EP disclosed
WO-2001017353-A1 HERBICIDAL COMPOSITION SYNGENTA PARTICIPATIONS AG (CH) 2001-03-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250057153-A1 Maleated Natural Oil Derivatives As Agrochemical Inert Ingredients MSL1, MGLL, NOTUM TSHR 4598/4885HTT 4297/4885SMN1; SMN2 2483/4885
US-20240059707-A1 PROCESS FOR THE PREPARATION OF PYRAZOLE-OXADIAZEPINE CYP3A4, OXA1L, CYP3A5 TSHR 3856/4885HTT 3490/4885SMN1; SMN2 2415/4885
US-12446576-B2 Agrochemical formulation containing a sulfopolymer ROS1, SQOR, RDX TSHR 4369/4885HTT 2880/4885SMN1; SMN2 1775/4885
US-20230329237-A1 MUSA PLANTS, FIELDS CONTAINING SUCH PLANTS KDM4C, CHRM4, METTL3 TSHR 1672/4885HTT 4332/4885SMN1; SMN2 2570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.