Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.40 |
| ▸ | ADH1B | P00325 | 1/20 | 0.40 |
| ▸ | ADH1C | P00326 | 1/20 | 0.40 |
| ▸ | ADH1A | P07327 | 1/20 | 0.40 |
| ▸ | ADH4 | P08319 | 1/20 | 0.40 |
| ▸ | ADH7 | P40394 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28353996 | 1.00 | TSHR (0.48) | TSHRALDH1A1ANPEPERAP2EPHX1 | |
| SCHEMBL24307673 | 0.98 | TSHR (0.50) | TSHRALDH1A1ANPEPERAP2EPHX1 | |
| SCHEMBL11195659 | 0.91 | TSHR (0.44) | TSHRALDH1A1ANPEPERAP2ADH1B | |
| SCHEMBL1668578 | 0.81 | TSHR (0.50) | TSHRALDH1A1ANPEPERAP2EPHX1 | |
| SCHEMBL1532449 | 0.81 | TSHR (0.50) | TSHRALDH1A1ANPEPERAP2EPHX1 | |
| SCHEMBL10495800 | 0.81 | TSHR (0.50) | TSHRALDH1A1ANPEPERAP2EPHX1 | |
| SCHEMBL987948 | 0.81 | TSHR (0.50) | TSHRALDH1A1ANPEPERAP2EPHX1 | |
| SCHEMBL27630548 | 0.80 | ANPEP (0.46) | TSHRALDH1A1ANPEPERAP2EPHX1 | |
| SCHEMBL8116246 | 0.80 | ANPEP (0.46) | TSHRALDH1A1ANPEPERAP2EPHX1 | |
| SCHEMBL27867243 | 0.80 | ANPEP (0.46) | TSHRALDH1A1ANPEPERAP2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075345-A1 | Novel inhibitor compounds specific of secreted non-pancreatic human a<sb>2</sb>phospholipase of group II | YANG JI CHEMICAL COMPANY LTD. (KR) | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075345-A1 | Novel inhibitor compounds specific of secreted non-pancreatic human a<sb>2</sb>phospholipase of group II | AMY2A, PNLIP, IAPP | TSHR 1834/4885ALDH1A1 3782/4885ANPEP 139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.