Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4148049 | 0.81 | BLM (0.53) | TSHRCYP2C19CYP3A4MEN1KMT2A | |
| SCHEMBL227064 | 0.80 | BLM (0.37) | RAB9ATSHRCYP2C19CYP3A4MEN1 | |
| SCHEMBL17371937 | 0.74 | MEN1 (0.50) | RAB9ATSHRUSP2CYP2C19CYP3A4 | |
| SCHEMBL1205421 | 0.73 | MAOA (0.42) | TSHRCYP2C19CYP3A4CYP1A2MEN1 | |
| SCHEMBL6643278 | 0.73 | FDPS (0.47) | FDPSRAB9ATSHRMEN1KMT2A | |
| SCHEMBL3680427 | 0.73 | FDPS (0.47) | FDPSRAB9ATSHRMEN1KMT2A | |
| SCHEMBL3236715 | 0.72 | FDPS (0.53) | FDPSRAB9ATSHRCYP2C19CYP3A4 | |
| SCHEMBL8266516 | 0.70 | BLM (0.66) | FDPSRAB9ATSHRUSP2CYP2C19 | |
| SCHEMBL31036573 | 0.70 | BLM (0.66) | FDPSRAB9ATSHRUSP2CYP2C19 | |
| SCHEMBL19921435 | 0.70 | CYP2C9 (0.49) | RAB9ATSHRUSP2CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867299-B2 | Inosine monophosphate dehydrogenase (IMPDH); use as immunosuppressants, anticancer agents and antiviral agents | HOFFMANN-LA ROCHE INC. (US) | 2005-03-15 | — | — | US | disclosed |