Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6501772 | 0.93 | PIK3C2B (0.47) | ALDH1A1MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL6502915 | 0.90 | SMN1; SMN2 (0.44) | ALDH1A1MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL6488906 | 0.90 | MEN1 (0.40) | ALDH1A1MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL6492166 | 0.90 | GAA (0.43) | ALDH1A1MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL6503536 | 0.90 | MCL1 (0.46) | PLA2G2AMCL1PPARGDCTPP1 | |
| SCHEMBL6488241 | 0.89 | MCL1 (0.43) | ALDH1A1MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL6499832 | 0.88 | PLA2G2A (0.42) | ALDH1A1MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL6491512 | 0.88 | MCL1 (0.41) | ALDH1A1MAPTHSD17B10PLA2G2ACYSLTR2 | |
| SCHEMBL6488675 | 0.88 | PLA2G2A (0.41) | ALDH1A1MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL6487942 | 0.88 | MCL1 (0.42) | PLA2G2ACYSLTR2CYSLTR1GAAMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | ALDH1A1 96/4885MAPT 3168/4885KDM4E 760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.