Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 5/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7777113 | 0.82 | KCNN4 (0.44) | KCNN4KCNE1KCNQ1CCR6CES2 | |
| SCHEMBL30757407 | 0.79 | KCNN4 (0.41) | KCNN4KCNE1KCNQ1CES2CES1 | |
| SCHEMBL1600455 | 0.79 | KCNN4 (0.41) | KCNN4KCNE1KCNQ1CES2CES1 | |
| SCHEMBL7206142 | 0.78 | PDK1 (0.42) | KCNN4KCNE1KCNQ1CCR6CES2 | |
| SCHEMBL5331319 | 0.78 | KCNN4 (0.41) | KCNN4KCNE1KCNQ1CCR6CES2 | |
| SCHEMBL24901411 | 0.78 | MEN1 (0.46) | KCNN4KCNE1KCNQ1PDK2PDK1 | |
| SCHEMBL2974843 | 0.77 | KCNN4 (0.44) | KCNN4KCNE1KCNQ1CES2CES1 | |
| SCHEMBL169053 | 0.76 | SLC22A12 (0.46) | KCNN4ALDH1A1ACHESLC22A12 | |
| SCHEMBL29466225 | 0.76 | SLC22A12 (0.46) | KCNN4ALDH1A1ACHESLC22A12 | |
| SCHEMBL10602905 | 0.76 | KCNN4 (0.42) | KCNN4KCNE1KCNQ1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050256177-A1 | Phenyl derivatives for the treatment of abnormal cell growth | PFIZER INC | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256177-A1 | Phenyl derivatives for the treatment of abnormal cell growth | CCND3, CDC25C, CCNA1 | KCNN4 3144/4885KCNE1 3618/4885KCNQ1 3210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.