Sugi Predict

Sugi Predict / Compounds / SCHEMBL648960

SCHEMBL648960

SCHEMBL648960

CC(C)COC(=O)O[C@H](c1ccc(S(C)(=O)=O)cc1)[C@@H](CF)NC(=O)C(Cl)Cl

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 4/20 0.60
▸ LMNA P02545 2/20 0.60
▸ MEN1 O00255 1/20 0.60
▸ KMT2A Q03164 1/20 0.60
▸ TSHR P16473 1/20 0.50
▸ CTSK P43235 6/20 0.34
▸ CTSS P25774 5/20 0.34
▸ CTSL P07711 4/20 0.34
▸ RPLP1 P05386 1/20 0.33
▸ RPLP0 P05388 1/20 0.33
▸ RPS17 P08708 1/20 0.33
▸ RPSA P08865 1/20 0.33
▸ RPS2 P15880 1/20 0.33
▸ RPL35A P18077 1/20 0.33
▸ RPL7 P18124 1/20 0.33
▸ RPL17 P18621 1/20 0.33
▸ RPS4Y1 P22090 1/20 0.33
▸ RPS3 P23396 1/20 0.33
▸ RPS12 P25398 1/20 0.33
▸ RPL13 P26373 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL648962 1.00 CYP3A4 (0.60) CYP3A4LMNAMEN1KMT2ATSHR
SCHEMBL10124444 0.94 CYP3A4 (0.58) CYP3A4LMNAMEN1KMT2ATSHR
SCHEMBL10124441 0.92 CYP3A4 (0.64) CYP3A4LMNAMEN1KMT2ATSHR
SCHEMBL652244 0.90 CYP3A4 (0.64) CYP3A4LMNAMEN1KMT2ATSHR
SCHEMBL652758 0.90 LMNA (0.70) CYP3A4LMNAMEN1KMT2ATSHR
SCHEMBL648631 0.90 CYP3A4 (0.58) CYP3A4LMNAMEN1KMT2ATSHR
SCHEMBL2322568 0.90 CYP3A4 (0.58) CYP3A4LMNAMEN1KMT2ATSHR
SCHEMBL648630 0.90 CYP3A4 (0.58) CYP3A4LMNAMEN1KMT2ATSHR
SCHEMBL651759 0.89 LMNA (0.63) CYP3A4LMNAMEN1KMT2ATSHR
SCHEMBL651760 0.89 LMNA (0.63) CYP3A4LMNAMEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8119667-B2 Carbonates of fenicol antibiotics SCHERING-PLOUGH ANIMAL HEALTH CORPORATION (US) 2012-02-21 — — US claimed
EP-1966129-B1 CARBONATES OF FENICOL ANTIBIOTICS SCHERING PLOUGH LTD (CH) 2011-08-17 — — EP claimed
US-8119667-B2 Carbonates of fenicol antibiotics SCHERING-PLOUGH ANIMAL HEALTH CORPORATION (US) 2012-02-21 — — US disclosed
US-8119667-B2 Carbonates of fenicol antibiotics SCHERING-PLOUGH ANIMAL HEALTH CORPORATION (US) 2012-02-21 — — US disclosed
EP-1966129-B1 CARBONATES OF FENICOL ANTIBIOTICS SCHERING PLOUGH LTD (CH) 2011-08-17 — — EP disclosed
EP-1966129-A2 CARBONATES OF FENICOL ANTIBIOTICS Schering-Plough Ltd. (CH) 2008-09-10 — — EP disclosed
WO-2007079010-A2 CARBONATES OF FENICOL ANTIBIOTICS SCHERING-PLOUGH LTD. (CH) 2007-07-12 — — WO disclosed
US-20070155799-A1 CARBONATES OF FENICOL ANTIBIOTICS INTERVET INC. 2007-07-05 — — US disclosed
US-20070155799-A1 CARBONATES OF FENICOL ANTIBIOTICS INTERVET INC. 2007-07-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070155799-A1 CARBONATES OF FENICOL ANTIBIOTICS CYP4F3, TET1, CYP4F2 CYP3A4 28/4885LMNA 2548/4885MEN1 1940/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.