Sugi Predict

Sugi Predict / Compounds / SCHEMBL651759

SCHEMBL651759

SCHEMBL651759

CCOC(=O)O[C@H](c1ccc(S(C)(=O)=O)cc1)[C@@H](CF)NC(=O)C(Cl)Cl

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.63
▸ CYP3A4 P08684 2/20 0.63
▸ MEN1 O00255 1/20 0.63
▸ KMT2A Q03164 1/20 0.63
▸ TSHR P16473 2/20 0.52
▸ RPLP1 P05386 1/20 0.34
▸ RPLP0 P05388 1/20 0.34
▸ RPS17 P08708 1/20 0.34
▸ RPSA P08865 1/20 0.34
▸ RPS2 P15880 1/20 0.34
▸ RPL35A P18077 1/20 0.34
▸ RPL7 P18124 1/20 0.34
▸ RPL17 P18621 1/20 0.34
▸ RPS4Y1 P22090 1/20 0.34
▸ RPS3 P23396 1/20 0.34
▸ RPS12 P25398 1/20 0.34
▸ RPL13 P26373 1/20 0.34
▸ RPL10 P27635 1/20 0.34
▸ RPL12 P30050 1/20 0.34
▸ RPL9; RPL9P7; RPL9P8; RPL9P9 P32969 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL651760 1.00 LMNA (0.63) LMNACYP3A4MEN1KMT2ATSHR
SCHEMBL652244 0.92 CYP3A4 (0.64) LMNACYP3A4MEN1KMT2ATSHR
SCHEMBL652758 0.92 LMNA (0.70) LMNACYP3A4MEN1KMT2ATSHR
SCHEMBL648811 0.92 CYP3A4 (0.60) LMNACYP3A4MEN1KMT2ATSHR
SCHEMBL648812 0.92 CYP3A4 (0.60) LMNACYP3A4MEN1KMT2ATSHR
SCHEMBL2365549 0.91 LMNA (0.51) LMNACYP3A4MEN1KMT2ATSHR
SCHEMBL649986 0.91 LMNA (0.68) LMNACYP3A4MEN1KMT2ATSHR
SCHEMBL650299 0.91 LMNA (0.68) LMNACYP3A4MEN1KMT2ATSHR
SCHEMBL10124495 0.91 LMNA (0.57) LMNACYP3A4MEN1KMT2ATSHR
SCHEMBL650296 0.91 LMNA (0.57) LMNACYP3A4MEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210355304-A1 RUBBER COMPOSITION FOR DYNAMIC USES, PRODUCTION METHOD THEREOF, PRODUCTS CONTAINING SAME, AND USES THEREOF HUTCHINSON (FR) 2021-11-18 — — US claimed
EP-3863865-A2 RUBBER COMPOSITION FOR DYNAMIC USES, PRODUCTION METHOD THEREOF, PRODUCTS CONTAINING SAME, AND USES THEREOF HUTCHINSON (FR) 2021-08-18 — — EP claimed
US-8119667-B2 Carbonates of fenicol antibiotics SCHERING-PLOUGH ANIMAL HEALTH CORPORATION (US) 2012-02-21 — — US claimed
EP-1966129-B1 CARBONATES OF FENICOL ANTIBIOTICS SCHERING PLOUGH LTD (CH) 2011-08-17 — — EP claimed
EP-0404888-B1 PLASTIC LENS COMPOSITIONS AND APPARATUS FOR THE PRODUCTION THEREOF 2100 INC Q (US) 1999-08-18 — — EP claimed
US-5153348-A Ester exchanging a choline salt with carbonate esters in aprotic solvents and solidification LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1992-10-06 — — US claimed
EP-0436516-A2 Optical devices for reducing photophobia CAMBRIDGE OPTICAL GROUP LIMITED (GB) 1991-07-10 — — EP claimed
JP-63041529-A — — None — — JP disclosed
US-20210355304-A1 RUBBER COMPOSITION FOR DYNAMIC USES, PRODUCTION METHOD THEREOF, PRODUCTS CONTAINING SAME, AND USES THEREOF HUTCHINSON (FR) 2021-11-18 — — US disclosed
EP-3863865-A2 RUBBER COMPOSITION FOR DYNAMIC USES, PRODUCTION METHOD THEREOF, PRODUCTS CONTAINING SAME, AND USES THEREOF HUTCHINSON (FR) 2021-08-18 — — EP disclosed
WO-2021153374-A1 AZO COMPOUND OR SALT THEREOF, AND DYE-BASED POLARIZING FILM, DYE-BASED POLARIZING PLATE AND DISPLAY DEVICE EACH CONTAINING SAME 日本化薬株式会社 2021-08-05 — — WO disclosed
WO-2021132166-A1 METHOD FOR PRODUCING ERIBULIN-BASED ANTIBODY-DRUG CONJUGATE エーザイ・アール・アンド・ディー・マネジメント株式会社 2021-07-01 — — WO disclosed
US-11024882-B2 Electrolytic solution for secondary battery, secondary battery, battery pack, electrically driven vehicle, power storage system, electrically driven tool, and electronic device MURATA MANUFACTURING CO., LTD. (JP) 2021-06-01 — — US disclosed
EP-0129478-A2 2-Sulfamoylbenzo (b) thiophene derivatives, their preparation and pharmaceutical composition for the treatment of elevated intraocular pressure MERCK & CO. INC. (US) 1984-12-27 — — EP disclosed
US-4486444-A CARBONIC ANHYDRASE INHIBITORS MERCK & CO., INC. (US) 1984-12-04 — — US disclosed
EP-0122178-A2 Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure MERCK & CO. INC. (US) 1984-10-17 — — EP disclosed
US-4477466-A Acyloxy derivatives of [phenylsulfonyl(or sulfinyl)]thiophenesulfonamide for the topical treatment of elevated intraocular pressure MERCK & CO., INC. (US) 1984-10-16 — — US disclosed
US-4414377-A Epoxide resin compositions containing esters as diluents and cure accelerators CIBA-GEIGY CORPORATION (US) 1983-11-08 — — US disclosed
US-4387237-A DECOMPOSITION OF B-HALOALKYL CARBONATES THE DOW CHEMICAL COMPANY (US) 1983-06-07 — — US disclosed
US-4058466-A FIRE RETARDANT HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1977-11-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11024882-B2 Electrolytic solution for secondary battery, secondary battery, battery pack, electrically driven vehicle, power storage system, electrically driven tool, and electronic device HCN2, HCN1, VDAC2 LMNA 2556/4885CYP3A4 2414/4885MEN1 2601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.