Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503545 | 0.93 | MCL1 (0.43) | KMT2AMCL1PLA2G2ACYSLTR2CYSLTR1 | |
| SCHEMBL6498711 | 0.92 | MCL1 (0.43) | LMNASMN1; SMN2MEN1KMT2AMCL1 | |
| SCHEMBL6502915 | 0.91 | SMN1; SMN2 (0.44) | LMNASMN1; SMN2MEN1KMT2AMCL1 | |
| SCHEMBL6489678 | 0.91 | MCL1 (0.41) | MCL1PLA2G2ACYSLTR2CYSLTR1BRD4 | |
| SCHEMBL6490973 | 0.90 | SMN1; SMN2 (0.43) | LMNASMN1; SMN2MEN1KMT2AMCL1 | |
| SCHEMBL6499497 | 0.89 | SMN1; SMN2 (0.42) | LMNASMN1; SMN2MEN1KMT2AMCL1 | |
| SCHEMBL6502885 | 0.88 | SMN1; SMN2 (0.42) | LMNASMN1; SMN2MEN1KMT2AMCL1 | |
| SCHEMBL6488064 | 0.87 | SMN1; SMN2 (0.41) | LMNASMN1; SMN2MEN1KMT2AMCL1 | |
| SCHEMBL6495218 | 0.87 | PDE3B (0.46) | LMNASMN1; SMN2MEN1KMT2APLA2G2A | |
| SCHEMBL6488241 | 0.85 | MCL1 (0.43) | KMT2AMCL1PLA2G2ACYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | LMNA 3711/4885SMN1; SMN2 1128/4885MEN1 1604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.