Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6500625 | 0.91 | FFAR1 (0.45) | PDE3BPDE3AP2RY12LMNASMN1; SMN2 | |
| SCHEMBL6495068 | 0.91 | PPARG (0.52) | PDE3BPDE3AP2RY12LMNASMN1; SMN2 | |
| SCHEMBL6490102 | 0.87 | LMNA (0.43) | LMNASMN1; SMN2PPARGPLA2G2AMEN1 | |
| SCHEMBL6498632 | 0.86 | PDE3B (0.48) | PDE3BPDE3AP2RY12LMNAPPARG | |
| SCHEMBL6503545 | 0.83 | MCL1 (0.43) | PDE3BPDE3AP2RY12PLA2G2AKMT2A | |
| SCHEMBL6497461 | 0.83 | PPARG (0.49) | PDE3BPDE3AP2RY12LMNAPPARG | |
| SCHEMBL6500673 | 0.81 | PPARG (0.49) | PDE3BPDE3AP2RY12LMNAPPARG | |
| SCHEMBL6489678 | 0.81 | MCL1 (0.41) | PDE3BPDE3AP2RY12PLA2G2ACYSLTR2 | |
| SCHEMBL6501536 | 0.81 | PPARG (0.52) | PDE3BPDE3AP2RY12LMNASMN1; SMN2 | |
| SCHEMBL6487701 | 0.80 | PPARG (0.49) | PDE3BPDE3AP2RY12PPARGPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | PDE3B 411/4885PDE3A 733/4885P2RY12 2028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.