Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 6/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.41 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6498329 | 0.93 | MAPT (0.41) | BCL2MCL1PLA2G2ATRPM4ALOX5AP | |
| SCHEMBL6500310 | 0.91 | ALOX5AP (0.40) | TRPM4ALOX5APTP53MAPTVDR | |
| SCHEMBL6491428 | 0.89 | BCL2 (0.46) | BCL2MCL1PLA2G2AALOX5APTP53 | |
| SCHEMBL6488053 | 0.88 | BCL2 (0.43) | BCL2MCL1PLA2G2ATRPM4 | |
| SCHEMBL6499987 | 0.86 | MRGPRX4 (0.50) | BCL2MCL1PLA2G2AALOX5AP | |
| SCHEMBL6488725 | 0.86 | ALOX5AP (0.37) | ALOX5APTP53MAPTVDRNR1H4 | |
| SCHEMBL6488597 | 0.83 | BCL2 (0.50) | BCL2MCL1PLA2G2AALOX5AP | |
| SCHEMBL6500991 | 0.82 | ALOX5AP (0.42) | BCL2MCL1PLA2G2AALOX5APTP53 | |
| SCHEMBL6488587 | 0.82 | BCL2 (0.37) | BCL2MCL1TRPM4TP53MAPT | |
| SCHEMBL6491236 | 0.80 | ALOX5AP (0.45) | BCL2MCL1PLA2G2AALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | BCL2 774/4885MCL1 806/4885PLA2G2A 4801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.