Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.50 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | BCL2 | P10415 | 5/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6491428 | 0.91 | BCL2 (0.46) | ALOX5APPPARGBCL2MCL1PLA2G2A | |
| SCHEMBL6488968 | 0.91 | PPARG (0.50) | ALOX5APPPARGLMNA | |
| SCHEMBL6488597 | 0.90 | BCL2 (0.50) | ALOX5APPPARGBCL2MCL1PLA2G2A | |
| SCHEMBL7196721 | 0.89 | PPARG (0.46) | MRGPRX4ALOX5APPPARGNR4A2NR4A1 | |
| SCHEMBL6500552 | 0.86 | MRGPRX4 (0.49) | MRGPRX4ALOX5APNR4A2NR4A1NR4A3 | |
| SCHEMBL6490177 | 0.86 | BCL2 (0.42) | ALOX5APBCL2MCL1PLA2G2A | |
| SCHEMBL6491236 | 0.85 | ALOX5AP (0.45) | ALOX5APPPARGBCL2MCL1PLA2G2A | |
| SCHEMBL6500991 | 0.84 | ALOX5AP (0.42) | ALOX5APPPARGBCL2MCL1PLA2G2A | |
| SCHEMBL6309396 | 0.81 | S1PR1 (0.50) | MRGPRX4ALOX5APPPARGNR4A2NR4A1 | |
| SCHEMBL6501536 | 0.81 | PPARG (0.52) | ALOX5APPPARGMCL1PLA2G2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | MRGPRX4 2443/4885ALOX5AP 4663/4885PPARG 233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.