Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 10/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 10/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490353 | 1.00 | ADRB1 (0.56) | ADRB1ADRB3TDP1MAPTPDE10A | |
| SCHEMBL6486794 | 0.90 | ADRB1 (0.46) | ADRB1ADRB3 | |
| SCHEMBL6489074 | 0.89 | ADRB1 (0.60) | ADRB1ADRB3PDE10A | |
| Hydrochloric Acid SCHEMBL6492690 | 0.87 | ADRB1 (0.58) | ADRB1ADRB3PDE10A | |
| SCHEMBL6489063 | 0.87 | ADRB1 (0.58) | ADRB1ADRB3PDE10A | |
| SCHEMBL6489069 | 0.87 | ADRB1 (0.58) | ADRB1ADRB3PDE10A | |
| Hydrochloric Acid SCHEMBL6492687 | 0.87 | ADRB1 (0.58) | ADRB1ADRB3PDE10A | |
| Hydrochloric Acid SCHEMBL6486797 | 0.85 | ADRB1 (0.57) | ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL6538601 | 0.84 | ADRB1 (0.66) | ADRB1ADRB3 | |
| SCHEMBL6478525 | 0.83 | ADRB1 (0.53) | ADRB1ADRB3PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050043358-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-02-24 | — | — | US | disclosed |
| US-20020143034-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2002-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020143034-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | ADRB1, ADRB2, ADRB3 | ADRB1 1/4885ADRB3 3/4885TDP1 3342/4885 |
| US-20050043358-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | ADRB2, ADRB1, ADRB3 | ADRB1 2/4885ADRB3 3/4885TDP1 3843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.