Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490067 | 0.75 | ACHE (0.46) | NPC1ALDH1A1RAB9A | |
| SCHEMBL24225536 | 0.74 | HPGD (0.59) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL6479566 | 0.73 | LMNA (0.42) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4023586 | 0.72 | HPGD (0.56) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL9437297 | 0.72 | HPGD (0.56) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL4023584 | 0.72 | HPGD (0.56) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL19499466 | 0.72 | HPGD (0.56) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL9143624 | 0.71 | HPGD (0.55) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL3009629 | 0.71 | HPGD (0.55) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL3009626 | 0.71 | HPGD (0.55) | HPGDTSHRPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050119231-A1 | Quinolone antibacterial agents | ELLSWORTH EDMUND L (US) | 2005-06-02 | — | — | US | disclosed |
| US-20050107423-A1 | Quinolone antibacterial agents | ELLSWORTH EDMUND L (US) | 2005-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119231-A1 | Quinolone antibacterial agents | NQO2, MRPL21, TOP1 | HPGD 184/4885TSHR 4656/4885TDP1 1677/4885 |
| US-20050107423-A1 | Quinolone antibacterial agents | NQO2, MRPL21, TOP1 | HPGD 184/4885TSHR 4656/4885TDP1 1677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.